Results 81 to 90 of about 55,210 (284)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Formulation and organoleptic test of edamame-mackarel tuna sprinkle powder as a high protein supplementation for stunting

open access: yesAcTion: Aceh Nutrition Journal
Stunting can also reduce the quality of human resources. Developing regional foods with high protein content, such as edamame and mackerel tuna, can help reduce the prevalence of stunting.
Septi Nur Rachmawati   +2 more
doaj   +1 more source

The Peacemakers: Navigating the Intersection of Biblical Justice and Contemporary Policing [PDF]

open access: yes, 2019
For Christians seeking to enter the field of policing, the question of justice is answered by two separate sources. Conceptions of justice are presented by both the contemporary justice system and the Bible.
Brown, Nathan
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Indo-european 'laryngeals' and Hittite hinik-, heu-: some critical observations

open access: yesLinguistica, 1993
Referring to 'lex Eichner' 1 certain scholars2 teach that the he- of Hittite heu­ 'rain' (heu-/he-aw-)3 goes back ultimately to the lengthened e-grade (*H-ēy-) of a root *H2ey-, the zero-grade of which is attested by the Hittite nasal infix verb stem ...
Fredrik Otto Lindeman
doaj   +1 more source

Record Maximum Oscillation Frequency in C-face Epitaxial Graphene Transistors

open access: yes, 2013
The maximum oscillation frequency (fmax) quantifies the practical upper bound for useful circuit operation. We report here an fmax of 70 GHz in transistors using epitaxial graphene grown on the C-face of SiC.
Badmaev A.   +42 more
core   +3 more sources

Sprinkles

open access: yesKáñina, 2005
"Había una vez, en una caliente tarde de julio, periodo de vacaciones escolares, un par de niños inquietos quienes hicieron a su madre la típica y a la vez temida pregunta, Mami, ¡qué aburrido! ¿Qué hacemos?..."
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Influence of the frontal joint of the bitumen sheet on the final strength of the joint

open access: yesMATEC Web of Conferences, 2018
This article focuses on the frequently discussed topic how to make the frontal joints of bitumen sheets with coarse-grained surface coating. Bitumen sheets have a spill in the place of these joints.
Plachý Jan   +2 more
doaj   +1 more source

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