Results 11 to 20 of about 30,791 (266)

Widespread micronodular hepatic metastases of neuroendocrine tumor detected by [68Ga]DOTATATE PET/CT

open access: yesRadiology Case Reports, 2023
Neuroendocrine tumors (NET) encompass a diverse, heterogeneous group of neoplasms that originate from the secretory cells of the neuroendocrine system. These neoplasms typically express the somatostatin receptor (SSTR), which can be targeted by molecular
Julia C. D'Souza, MD, MS   +4 more
doaj   +1 more source

Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Arginase is a complex and unique enzyme that plays diverse roles in health and disease. By metabolizing arginine, it can shape the outcome of innate and adaptive immune responses. The immunomodulatory capabilities of arginase could potentially be applied
Makan Khoshnejad   +12 more
doaj   +1 more source

POT1-TPP1 telomere length regulation and disease

open access: yesComputational and Structural Biotechnology Journal, 2020
Telomeres are DNA repeats at the ends of linear chromosomes and are replicated by telomerase, a ribonucleoprotein reverse transcriptase. Telomere length regulation and chromosome end capping are essential for genome stability and are mediated primarily ...
Tomas Aramburu   +2 more
doaj   +1 more source

Dynamic contrast enhanced MRI for characterization of blood-brain-barrier dysfunction after traumatic brain injury

open access: yesNeuroImage: Clinical, 2022
Background and Purpose: Dysfunction of the blood–brain-barrier (BBB) is a recognized pathological consequence of traumatic brain injury (TBI) which may play an important role in chronic TBI pathophysiology.
Jeffrey B. Ware   +13 more
doaj   +1 more source

Hydroxyacetophenone defenses in white spruce against spruce budworm [PDF]

open access: yesEvolutionary Applications, 2019
AbstractWe review a recently discovered white spruce (Picea glauca) chemical defense against spruce budworm (Choristoneura fumiferana) involving hydroxyacetophenones. These defense metabolites detected in the foliage accumulate variably as the aglycons, piceol and pungenol, or the corresponding glucosides, picein and pungenin.
Parent, GJ   +7 more
openaire   +4 more sources

18F-FDG and 18F-NaF PET/CT Global Assessment of Large Joint Inflammation and Bone Turnover in Rheumatoid Arthritis

open access: yesDiagnostics, 2023
Rheumatoid arthritis (RA) involves chronic inflammation of synovial joints, causing pain, stiffness, and limited mobility. 18F-sodium fluoride (NaF) is a PET tracer whose uptake reflects bone turnover, while 18F-fludeoxyglucose (FDG) shows glucose ...
Natasha Reddy   +5 more
doaj   +1 more source

Clival mucocele: An unusual finding 17 years after endoscopic sinus surgery

open access: yesOtolaryngology Case Reports, 2022
Introduction: To describe a case of an isolated clival mucocele presenting asymptomatically after previous endoscopic sinus surgery and review the existing literature on the clinical characteristics associated with these lesions. Methods: Case report and
Nicholas A. Frisco   +3 more
doaj   +1 more source

Neuroform Atlas™ for treatment of symptomatic flow-limiting stenoses of the distal cervical ICA: Advantages of a fifth generation stent

open access: yesInterdisciplinary Neurosurgery, 2020
Cervical carotid artery dissections (CAD) usually produce ischemic symptoms as a result of thromboembolic phenomena, but hemodynamic insufficiency from flow-limiting stenosis can cause symptoms in a few patients [1].
Mougnyan Cox   +7 more
doaj   +1 more source

Interferon-α alters host glycosylation machinery during treated HIV infection

open access: yesEBioMedicine, 2020
Background: A comprehensive understanding of host factors modulated by the antiviral cytokine interferon-α (IFNα) is imperative for harnessing its beneficial effects while avoiding its detrimental side-effects during HIV infection.
Leila B. Giron   +16 more
doaj   +1 more source

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