Results 211 to 220 of about 2,082,669 (307)

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

open access: yesAdvanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu   +11 more
wiley   +1 more source

Glucosinolate and Isothiocyanate Profiles in Different Varieties of Raphanus sativus Seed via Multivariate Data Analysis

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Through HPLC–MS/MS analysis and multivariate statistics, raphani semen (RS) varieties with high functional components were screened. The white raphani semen “Xuebawang” was identified as ideal for further study due to its high bioactive content: glucoraphenin (9010.27 mg/100 g), glucoraphanin (1027.76 mg/100 g), sulforaphane (66.14 mg/100 g), and ...
Yonghua Li   +10 more
wiley   +1 more source

The Effect of Resistance Training and Ursolic Acid on the PI3K‐AKT‐mTOR Pathway in Aged Diabetic Rats: A Comparative Study

open access: yesAGING MEDICINE, EarlyView.
Resistance training combined with ursolic acid supplementation restores anabolic signaling (PI3K/mTORC1) suppressed by diabetes, helping preserve muscle mass. This strategy may offer a potential therapeutic approach to combat muscle atrophy and support healthy aging in diabetic conditions.
Ashkan Sadeghi   +4 more
wiley   +1 more source

SPSS for IBM CMS operations guide

open access: yes, 1990
SPSS, Inc. (Chicago, Ill.)
core  

Effect of Lactulose on the Intestinal Flora of Elderly Constipation Patients With Chronic Renal Insufficiency

open access: yesAGING MEDICINE, EarlyView.
This study investigates the regulatory effects of lactulose and polyethylene glycol (PEG) on the composition of gut microbiota in elderly constipation patients with chronic renal insufficiency by comparing the changes in microbial abundance. Both lactulose and PEG significantly modulate the gut microbiota structure, though their specific mechanisms and
Jianxia Ma   +10 more
wiley   +1 more source

Research Communication: The Cumulated Spontaneous Portosystemic Shunts (SPSS) Area Decreases After TIPS and Impacts on Prognosis. [PDF]

open access: yesAliment Pharmacol Ther
Hintersteininger M   +14 more
europepmc   +1 more source

Morbidity Among the Aging Population in Northern Bangladesh: An Epidemiological Study

open access: yesAGING MEDICINE, EarlyView.
Multimorbidity (≥ 2 chronic diseases) is common among aging populations, yet evidence from Bangladesh remains limited. A cross‐sectional survey of 540 older adults in Northern Bangladesh (June–August 2022) assessed multimorbidity using interviews and logistic regression analysis. Multimorbidity prevalence was 75.74% (95% CI: 71.9%–79.3%).
Md. Abu Sayem   +3 more
wiley   +1 more source

Prioritising Data Quality Governance for AI in Prostate Cancer: A Methodological Proof-of-Concept Study Using Neural Networks for Risk Stratification. [PDF]

open access: yesDiagnostics (Basel)
Talavera-Cobo V   +9 more
europepmc   +1 more source

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