Results 181 to 190 of about 149,319 (312)

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Supportive periodontal therapy: individual patients' perception of various professional interventions. [PDF]

BMC Oral Health
Cyris M, Kopetzki L, Schulte DM, Dörfer CE, Ehrenthal JC, Graetz C.   +5 more
europepmc   +1 more source

Early Detection of Lower Adherence to Long‐Term e‐Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?

Clinical &Experimental Allergy, EarlyView.
Adherence to e‐Diary reporting was investigated in a blended care setting among pollen allergic patients with heterogeneous cultural backgrounds. A stable ‘higher’ and a more variable ‘lower’ adherence cluster were identified. Early identification of lower adherence is possible and might inform early interventions to improve patient adherence. ABSTRACT
S. Dramburg, C. J. Hernandez Toro, U. Grittner, S. Tripodi, S. Arasi, A. Acar Şahin, X. Aggelidis, A. Barbalace, A. Bourgoin, B. Bregu, M. A. Brighetti, E. Caeiro, S. Caglayan Sozmen, L. Caminiti, D. Charpin, M. Couto, L. Delgado, A. Di Rienzo Businco, C. Dimier, M. V. Dimou, J. A. Fonseca, O. Goksel, D. Hernandez, T. M. Hoffmann, D. T. Jang, F. Kalpaklioglu, B. Lame, R. Llusar, M. Makris, A. Mazon, E. Mesonjesi, A. Nieto, A. Öztürk, L. Pahus, G. Pajno, I. Panasiti, N. G. Papadopoulos, E. Pellegrini, S. Pelosi, A. M. Pereira, M. Pereira, N. M. Pinar, E. Potapova, A. Priftanji, F. Psarros, C. Sackesen, I. Sfika, J. Suarez, M. Thibaudon, A. Travaglini, U. Uguz, V. Verdier, V. Villella, P. Xepapadaki, D. Yazici, P. M. Matricardi   +55 more
wiley   +1 more source

A novel role of BPCs in the control of medial domain differentiation during gynoecium development in Arabidopsis thaliana. [PDF]

Plant Mol Biol
Caselli F, Palermiti M, Petrella R, Morlacchi VA, Dünser K, Kleine-Vehn J, Chiara M, Gregis V.   +7 more
europepmc   +1 more source

Optimal urethral catheter removal time after robotic radical prostatectomy: a systematic review of the current evidence. [PDF]

Front Surg
Mourmouris P, Kostakopoulos N, Argun OB, Georgopoulos I, Klapsis V, Pisiotis N, Salmas I, Doganca T, Charamoglis S.   +8 more
europepmc   +1 more source

Health insurance and labor supply: Evidence from same‐sex couples

Contemporary Economic Policy, EarlyView.
Abstract This paper examines labor supply effects of policies allowing public sector workers to include same‐sex partners in employer‐sponsored insurance plans. Unlike broader partnership recognition rights, these policies focus narrowly on insurance access.
Elisabeth Wurm
wiley   +1 more source

Morphological evidence suggestive of a hierarchical mode of glial cell diversification and intrinsic developmental plasticity within the murine enteric nervous system. [PDF]

Front Neurosci
Lefèvre MA, Bourgeois M, Soret R, Pilon N.   +3 more
europepmc   +1 more source

Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition

The FEBS Journal, EarlyView.
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis, Abibe Useini, Heike Betat, Sonja Bonin, Helen Broghammer, Rima Nuwayhid, Stefan Langer, Mario Mörl, Norbert Sträter, John T. Heiker   +9 more
wiley   +1 more source

Effect of fines content on liquefaction resistance of soil using laboratory test and SPT. [PDF]

Sci Rep
Li K, Liu J, Mu C, Zhang Y, Ge L.
europepmc   +1 more source

His Majesty's Inspectorate of Prisons for England and Wales, the UK National Preventive Mechanism and the UN Optional Protocol for the Prevention of Torture. Prospects for Prison Reform and the Treatment of Prisoners

The Howard Journal of Crime and Justice, EarlyView.
ABSTRACT HM Chief Inspector of Prisons for England and Wales is mandated under domestic law to visit and report on prison conditions and the treatment of prisoners. The Inspectorate's detailed monitoring work provides valuable and authoritative insights into individual prison establishments as well as the overall conditions in prisons and the treatment
Isobel Renzulli
wiley   +1 more source