Results 71 to 80 of about 14,888,290 (302)

PENGENALAN POLA SIDIK JARI RIDGE ENDING DAN BIFURCATION POINT DENGAN EKSTRAKSI MINUSI METODE CROSSING NUMBER

Teknologi dan Kejuruan, 2012
: Biometric is a development of basic method of identification using human natural characteristics as its basic. One of the biometric system that is often used is fingerprint.
I Putu Dody Lesmana
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Our behavior can spur development

, 2020
Economy
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Genome sequencing of ‘Fuji’ apple clonal varieties reveals genetic mechanism of the spur-type morphology

Nature Communications
Somatic variations can give rise to bud sports with advantageous traits, serving as the foundation for bud sport breeding in perennial plants. Here, we report a fully phased genome assembly of ‘Fuji’ apple, enabling comprehensive identification of ...
Yudong Cai, Xiuhua Gao, Jiangping Mao, Yu Liu, Lu Tong, Xilong Chen, Yandong Liu, Wenyan Kou, Chuanjun Chang, Toshi Foster, Jialong Yao, Amandine Cornille, Muhammad Mobeen Tahir, Zhi Liu, Zhongye Yan, Siyi Lin, Fengwang Ma, Juanjuan Ma, Libo Xing, Na An, Xiya Zuo, Yanrong Lv, Zhengyang Zhao, Wenqiang Li, Qianjin Li, Caiping Zhao, Yanan Hu, Hangkong Liu, Chao Wang, Xueyan Shi, Doudou Ma, Zhangjun Fei, Yu Jiang, Dong Zhang   +33 more
doaj   +1 more source

Development Effectiveness Overview (DEO) 2024

The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

IDB Newsletter: Vol. 7, no. 4, October 1969

, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Democracy with adjectives? Economic development and democracy in the Middle East

Frontiers in Political Science
Shadi Hamid, in his book “The Problem of Democracy, advocates for the promotion of minimalist democracy for the Middle East. Can minimalist democracy respond to the aspirations of the Arab public?
Salih Yasun
doaj   +1 more source