Results 31 to 40 of about 74,649 (269)

Effects of waterway regulation structures on the planktonic community in the upper Yangtze River

open access: yesEcological Indicators, 2023
To investigate the effects of the waterway regulation structures on the hydraulic characteristics, water physicochemical factors, and the planktonic community in the upper Yangtze River, this study was conducted in August and September of 2022 on two ...
Yu Wan   +5 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Local scour around spur dikes under ice-jammed flow conditions

open access: yesScientific Reports
The occurrence of ice jams in rivers in cold regions during winter complicates the local scour process around spur dikes. In this study, laboratory experiments were conducted to investigate the effects of flow Froude number, ice–water flow ratio, the ...
Shiwen Cheng   +3 more
doaj   +1 more source

Numerical Design and Preliminary Evaluation of a U-Shaped Hydraulic Flume for Flood Early Warning Applications [PDF]

open access: yesE3S Web of Conferences
The present study introduces the design and preliminary evaluation of a U-shaped hydraulic flume aimed at supporting flood early warning systems. Numerical simulations were employed to investigate flow characteristics under subcritical conditions, both ...
Patriadi Andi   +3 more
doaj   +1 more source

Experimental Investigation of The Effect of The Permeable Spur Dikes on Scour Hole Dimensions in a Mild 90 Degree Bend [PDF]

open access: yesعلوم و مهندسی آبیاری, 2016
Utilizing spur dikes is one of the common methods of organizing and controlling side erosion in river bends. In this research study the effect of permeability of spur dike on scour-hole dimensions was experimentally investigated in a flume with 0.7m ...
Maryam Shahabi   +1 more
doaj   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

Three-dimensional numerical simulation of local scour based on spur dikes in a natural river

open access: yesShuili Shuiyun Gongcheng Xuebao, 2020
In order to study the influences of the spur dike length on the local scour of riverbed in the natural rivers, based on the shape of the natural river channels and the actual layout of the spur dikes, a three-dimensional computational fluid dynamics (CFD)
QI Lan, ZENG Qingda, JI Shunwen
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Design Procedures and Field Monitoring of Submerged Barbs for Streambank Protection: TR-534, June 2007 [PDF]

open access: yes, 2007
The main objective of this study was to evaluate the hydraulic performance of riprap spurs and weirs in controlling bank erosion at the Southern part of the Raccoon River upstream U.S. Highway 169 Bridge utilizing the commercially available model FESWMS

core  

Experimental investigation of flow pattern around repelling and attracting T-head spur dikes on flat bed [PDF]

open access: yes, 2017
Use of T-head spur dikes is one of the common methods to control erosion of riverbanks. Nevertheless, setting spur dikes in the flow direction leads to modification of flow path and local scour in the site of the spur dike.
Abadi, A. Mahdieh Najaf, Bateni, M.M.
core   +1 more source

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