Results 31 to 40 of about 806,362 (263)
Objective: With the increasing incidence and mortality of laryngeal squamous cell carcinoma worldwide, researchers continue to search for novel prognostic factors and treatment methods for preventing early laryngeal squamous cell carcinoma from becoming ...
Li Luo, Honggang Liu
doaj +1 more source
Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort. [PDF]
Purpose Treatment with pembrolizumab, an anti-programmed death-1 antibody, at 10 mg/kg administered once every 2 weeks, displayed durable antitumor activity in programmed death-ligand 1 (PD-L1) -positive recurrent and/or metastatic (R/M) head and neck ...
Berger, Raanan +21 more
core +2 more sources
Subungual squamous cell carcinoma [PDF]
Although subungual squamous cell carcinoma is rare, it is the most common primary malignant neoplasms in this location. The higher incidence occurs in the fingernails, but involvement of the toenails is also possible. Subungual squamous cell carcinoma often looks like other more common benign lesions, such as fungal infection, onychomycosis, or viral ...
Padilha, Carolina Barbosa de Sousa +5 more
openaire +5 more sources
Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O. +3 more
core +2 more sources
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources
Infundibulocystic Squamous Cell Carcinoma [PDF]
Infundibulocystic squamous cell carcinoma was first reported in 2008 as a subset of squamous cell carcinoma arising from the infundibulum of the hair follicle and exhibiting infundibular differentiation. It has well-differentiated, less-differentiated, and infiltrative forms. It was thoroughly analyzed in a series of cases in 2011 by Misago et al.
Kim, So Min +4 more
openaire +2 more sources
Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
Squamous cell lung cancer maintains its growth through elevated glucose consumption, but selective glucose consumption inhibitors are lacking. Here, we discovered using a high-throughput screen new compounds that block glucose consumption in three ...
Chiara Ghezzi +3 more
doaj +1 more source
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Introduction: Oral squamous cell carcinoma (OSCC), which accounts for a high proportion of oral cancers, is characterized by high aggressiveness and rising incidence. Lysine acetylation is associated with cancer pathogenesis.
Shi-Zhou Deng +4 more
doaj +1 more source
Objective Tongue squamous cell carcinoma is one of the most common oral tumors. Human papillomavirus (HPV) infection has been proposed as a risk factor for head and neck squamous cell carcinoma, particularly oropharyngeal squamous carcinoma.
Kunsong Huang +9 more
doaj +1 more source

