Results 181 to 190 of about 1,404,226 (404)

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Simultaneous Laryngeal Squamous Cell Carcinoma and Papillary Thyroid Carcinoma

Middle East Journal of Cancer, 2011
The association of squamous cell carcinoma of the larynx with thyroid papillary carcinoma is an unusual finding. From 2004 to 2011, approximately 250 patients underwent laryngectomies due to squamous cell carcinoma of the larynx at the Otolaryngology ...
Bighan Khademi, Negar Azarpira, Mehr Sadat Alavi, Mohamad Javad Ashraf   +3 more
doaj  

Expression of long non-coding RNA SFTA1P and its effect on biological functions in lung squamous cell carcinoma

陆军军医大学学报
Objective To investigate the expression of long non-coding RNA (lncRNA), surfactant associated 1 pseudogene (SFTA1P) in lung squamous carcinoma and its effect on the biological functions of SFTA1P in lung squamous carcinoma cell lines.
WAN Weiping, XIE Weijia, XIA Tingting
doaj   +1 more source

CHEMICAL STUDIES ON THE TRANSFORMATION OF MOUSE EPIDERMIS BY METHYLCHOLANTHRENE TO SQUAMOUS CELL CARCINOMA

, 1944
Christopher Carruthers, V. Suntzeff
openalex   +1 more source

Unveiling Macrophage Content as a Predictive Biomarker for Intraoperative ICG Imaging Efficacy in Lung Cancer

Advanced Science, EarlyView.
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan, Jiahui Mi, Yun Li, Guanchao Jiang, Yimeng Zhang, Yanguo Liu, Hui Zhao, Jianfeng Li, Xing Yang, Jun Wang, Fan Yang, Kezhong Chen, Yiguang Wang, Jian Zhou   +13 more
wiley   +1 more source

Helicobacter Pylory infection in patients with esophageal squamous cell carcinoma

Clinics
OBJECTIVE: Esophageal squamous cell carcinoma is one of the most common esophageal diseases in the developing world, but the relationship between esophageal squamous cell carcinoma and Helicobacter pylori infection remains a neglected topic.
Omer Bilgehan Poyrazoglu, Ahmet Cumhur Dulger, Bilge Sumbul Gultepe   +2 more
doaj   +1 more source

An analysis of 100 cases of squamous-cell carcinoma of the esophagus.I. with special reference to the delay periods and delay factors in diagnosis and therapy, contrasting state and city and county institutions

, 1952
K. Alvin Merendino, Vernon H. Mark
openalex   +1 more source

Squamous Cell Carcinoma of the Oral Tongue: a Single Institution Retrospective Cohort Study From Mansoura University Hospital [PDF]

, 2019
Background: Egyptian hospital–based statistics showed that head & neck carcinomas represent 18% of all cancers and mostly diagnosed at advanced stages.
Halim, A. (Amal), Hamdy, R. (Rasha)
core  

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source

Infiltrative squamous cell (epidermoid) carcinoma of vulva [PDF]

, 1961
John Gosling, Murray R. Abell, Bernadette M. Drolette, T. D. Loughrin   +3 more
openalex   +1 more source