Results 191 to 200 of about 1,427,322 (409)

FDFT1 repression by piR-39980 prevents oncogenesis by regulating proliferation and apoptosis through hypoxia in tongue squamous cell carcinoma

, 2023
Trisha Chattopadhyay, Bibekanand Mallick
openalex   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Cancer‑associated fibroblast‑derived exosomal miR‑382‑5p promotes the migration and invasion of oral squamous cell carcinoma

, 2019
Liping Sun, Kai Xu, Jing Cui, Dao‐Ying Yuan, Bo Zou, Jun Li, Jianlin Liu, Ke‐Yi Li, Zhen Meng, Bin Zhang   +9 more
openalex   +2 more sources

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

Science, 2011
Nicolas Stransky, A. Egloff, Aaron D. Tward, Aleksandar D. Kostic, K. Cibulskis, A. Sivachenko, G. Kryukov, M. Lawrence, C. Sougnez, A. McKenna, Erica Shefler, A. Ramos, P. Stojanov, S. Carter, Douglas Voet, M. Cortés, Daniel Auclair, Michael F. Berger, G. Saksena, C. Guiducci, R. Onofrio, Melissa Parkin, M. Romkes, J. Weissfeld, Raja R. Seethala, Lin Wang, C. Rangel-Escareño, J. Fernández-López, A. Hidalgo-Miranda, J. Meléndez-Zajgla, W. Winckler, K. Ardlie, S. Gabriel, M. Meyerson, Eric S. Lander, G. Getz, Todd R. Golub, Levi A. Garraway, J. Grandis   +38 more
semanticscholar   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Simultaneous Laryngeal Squamous Cell Carcinoma and Papillary Thyroid Carcinoma

Middle East Journal of Cancer, 2011
The association of squamous cell carcinoma of the larynx with thyroid papillary carcinoma is an unusual finding. From 2004 to 2011, approximately 250 patients underwent laryngectomies due to squamous cell carcinoma of the larynx at the Otolaryngology ...
Bighan Khademi, Negar Azarpira, Mehr Sadat Alavi, Mohamad Javad Ashraf   +3 more
doaj  

Silencing PFKP inhibits starvation-induced autophagy, glycolysis, and epithelial mesenchymal transition in oral squamous cell carcinoma

, 2018
Guanhui Chen, Haichao Liu, Yadong Zhang, Jianfeng Liang, Yue Zhu, Ming Zhang, Dongsheng Yu, Cheng Wang, Jinsong Hou   +8 more
openalex   +1 more source

Nab‐paclitaxel‐based compared to docetaxel‐based induction chemotherapy regimens for locally advanced squamous cell carcinoma of the head and neck [PDF]

, 2015
Amy E. Schell, Jessica Ley, Ningying Wu, Kathryn Trinkaus, Tanya M. Wildes, Loren S. Michel, Wade L. Thorstad, Hiram A. Gay, James S. Lewis, Jason T. Rich, Jason Diaz, Randal C. Paniello, Brian Nussenbaum, Douglas R. Adkins   +13 more
openalex   +1 more source

Lrig1expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth [PDF]

, 2021
Laura Succony, Sandra Gómez‐López, Adam Pennycuick, Ahmed S. N. Alhendi, Derek Davies, Sarah E. Clarke, Kate H.C. Gowers, Nicholas A. Wright, Kim B. Jensen, Sam M. Janes   +9 more
openalex   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source