Results 231 to 240 of about 1,427,322 (409)

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Is molecular testing necessary for squamous cell carcinoma? [PDF]

Oncologist
Nishimura T, Fujimoto H.
europepmc   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma. [PDF]

Nat Commun
Tandukar B, Deivendran D, Chen L, Bandari AK, Cruz-Pacheco N, Sharma H, Wang M, Xu A, Chen DB, George CD, Marty AL, Cho RJ, Cheng JB, Saylor D, Gerami P, Yeh I, Arron ST, Bastian BC, Shain AH.   +18 more
europepmc   +1 more source

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

Science, 2011
N. Agrawal, M. Frederick, C. Pickering, C. Bettegowda, K. Chang, Ryan J Li, C. Fakhry, T. Xie, Jiexin Zhang, Jing Wang, Nianxiang Zhang, A. El-Naggar, S. Jasser, J. Weinstein, L. Treviño, J. Drummond, D. Muzny, Yuanqing Wu, L. Wood, R. Hruban, W. Westra, W. Koch, J. Califano, R. Gibbs, D. Sidransky, B. Vogelstein, V. Velculescu, N. Papadopoulos, D. Wheeler, K. Kinzler, J. Myers   +30 more
semanticscholar   +1 more source

Staging and grading of oral squamous cell carcinoma: An update.

Oral Oncology, 2020
A. Almangush, A. Mäkitie, A. Triantafyllou, R. de Bree, P. Strojan, A. Rinaldo, J. Hernandez-Prera, C. Suárez, L. Kowalski, A. Ferlito, I. Leivo   +10 more
semanticscholar   +1 more source

SERS‐AI‐LUA‐Driven Salivary Diagnosis of Head and Neck Cancer Using Graphene‐Assisted Plasmonic Nanocorals

Advanced Science, EarlyView.
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo, Boyou Heo, Jun‐Yeong Yang, Rowoon Park, Sung‐Gyu Park, Jiyoung Yeo, So Hee Park, Chan Kwon Jung, Min‐Young Lee, Jooin Bang, Jun‐Ook Park, Ho Sang Jung   +11 more
wiley   +1 more source

Squamous cell carcinoma in an umbilical cyst: a clinical image. [PDF]

Oxf Med Case Reports
Stevens JV, Aliniagerdroudbari E, Woghiren O, Neill D, Kim S, Isaacson A.   +5 more
europepmc   +1 more source

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

Squamous cell carcinoma of the sigmoid colon: a rare case report. [PDF]

J Surg Case Rep
Husain S, Aslam M.
europepmc   +1 more source