Results 31 to 40 of about 1,404,226 (404)

Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]

, 2016
The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita, Deng, Wenbing, Gong, Wenrong, Qin, Xin, Yu, Hongjun, Zhang, Min   +5 more
core   +1 more source

SYNCHRONOUS SQUAMOUS CELL CARCINOMA OF EXTERNAL ACOUSTIC MEATUS FOLLOWING PIGMENTED BASAL CELL CARCINOMA OF CHEEK -A RARE OCCURRENCE

Bengal Journal of Otolaryngology and Head Neck Surgery, 2015
Introduction: A synchronous second primary malignancy as squamous cell carcinoma of external acoustic meatus following basal cell carcinoma of cheek is reported with their management and review of literature.
Debangshu Ghosh, Rajarshi Sannigrahi, Sumit Kumar Basu, Parna Basu   +3 more
doaj   +3 more sources

Oral squamous cell carcinoma of tongue: Histological risk assessment. A pilot study [PDF]

, 2019
Background: More than 90% of malignant tumors diagnosed in the oral cavity are Oral Squamous Cell Carcinomas (OSCC) whose preferred location is the tongue.
Cebrián Carretero, José Luis, López Sánchez, Antonio Francisco, Martínez García, Miguel Angel, Migueláñez Medrán, Carmen, Pozo Kreilinger, José Juan   +4 more
core   +3 more sources

Technical and clinical performance of a new assay to detect squamous cell carcinoma antigen levels for the differential diagnosis of cervical, lung, and head and neck cancer

Tumor Biology, 2018
In squamous cell carcinoma, squamous cell carcinoma antigen levels are often elevated. This multi-center study evaluated the technical performance of a new Elecsys ® squamous cell carcinoma assay, which measures serum squamous cell carcinoma antigen 1 ...
Stefan Holdenrieder, Rafael Molina, Ling Qiu, Xiuyi Zhi, Sandra Rutz, Christine Engel, Pia Kasper-Sauer, Farshid Dayyani, Catharina M Korse   +8 more
doaj   +1 more source

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma

Cell Death and Disease, 2021
Targeted therapy has greatly improved both survival and prognosis of cancer patients. However, while therapeutic treatment of adenocarcinoma has been advanced greatly, progress in treatment of squamous cell carcinoma (SCC) has been slow and ineffective ...
Jing Xu, Fengtian Li, Ya Gao, Rongtian Guo, Liangping Ding, Mengyuan Fu, Yong Yi, Hu Chen, Zhi-Xiong Jim Xiao, Mengmeng Niu   +9 more
doaj   +1 more source

Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus

Tumor Biology, 2017
Mounting evidence has demonstrated that Bit1 has been investigated as an etiological factor for certain cancers, including esophageal squamous cell carcinoma reported in our previous study, but data regarding possible roles of Bit1 in esophageal squamous
Jing Chen, Hongtao Liu, Pan Gao, Yiran Hui, Zhenzhen Yang, Xiaqing Zhang, Peirong Xu, Fang Tian, Tianli Fan   +8 more
doaj   +1 more source

Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment

Nature Communications, 2020
Cancer immunotherapy has revolutionized cancer treatment, and it relies heavily on the comprehensive understanding of the immune landscape of the tumor microenvironment (TME).
Yingxia Zheng, Zheyi Chen, Yichao Han, Li Han, Xin Zou, Bingqian Zhou, Rui Hu, Jie Hao, Shihao Bai, Hai-bo Xiao, W. Li, Alex Bueker, Yanhui Ma, Guo-hua Xie, Junyao Yang, Shiyu Chen, Hecheng Li, Jian Cao, Lisong Shen   +18 more
semanticscholar   +1 more source

PD‐1 Blockade with Cemiplimab in Advanced Cutaneous Squamous‐Cell Carcinoma

New England Journal of Medicine, 2018
Background No systemic therapies have been approved for the treatment of advanced cutaneous squamous‐cell carcinoma. This cancer may be responsive to immune therapy, because the mutation burden of the tumor is high and the disease risk is strongly ...
M. Migden, D. Rischin, C. Schmults, A. Guminski, A. Hauschild, K. Lewis, C. Chung, L. Hernandez-Aya, A. Lim, A. Chang, G. Rabinowits, A. Thai, L. Dunn, B. Hughes, N. Khushalani, B. Modi, D. Schadendorf, Bo Gao, F. Seebach, Siyu Li, Jingjin Li, M. Mathias, J. Booth, K. Mohan, E. Stankevich, H. Babiker, I. Braña, M. Gil-Martin, J. Homsi, M. Johnson, V. Moreno, J. Niu, T. Owonikoko, K. Papadopoulos, G. Yancopoulos, I. Lowy, M. Fury   +36 more
semanticscholar   +1 more source

Oral squamous cell carcinomas: state of the field and emerging directions

International Journal of Oral Science, 2023
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral cavity. It accounts for approximately 90% of oral malignancies and impairs appearance, pronunciation, swallowing, and flavor perception.
Yunhan Tan, Zhihan Wang, Mengtong Xu, Bowen Li, Zhao Huang, Siyuan Qin, Edouard C. Nice, Jing Tang, Canhua Huang   +8 more
semanticscholar   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O., Ferlito, Alfio, Hellquist, Henrik, Hunt, Jennifer L.   +3 more
core   +2 more sources