Results 91 to 100 of about 13,374 (242)

CAPZB mRNA is a novel biomarker for cervical high-grade squamous lesions

Scientific Reports
This study aimed to evaluate the potential of capping protein (actin filament) muscle Z-line subunit β (CAPZB) messenger ribonucleic acid (mRNA) levels as a biomarker for distinguishing low-grade squamous intraepithelial lesions of the cervix (LSIL) from
Xia Cai, Wanqiu Huang, Jian Huang, Xiuxiang Zhu, Lifeng Wang, Ziyin Xia, Ling Xu   +6 more
doaj   +1 more source

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm, Lotte Krog Eriksen, Kathrine Dyhr Lycke, Ninna Lund Larsen, Iben Sundtoft, Tina Hovgaard Randrup, Anne Hammer   +6 more
wiley   +1 more source

Human papillomaviral load changes in low-grade squamous intraepithelial lesions of the uterine cervix [PDF]

, 2006
[[abstract]]To better predict risk of progression of low-grade squamous intraepithelial lesions (LSILs) of the uterine cervix in women with human papillomavirus (HPV) infections, 294 baseline cervical specimens from women with LSILs were evaluated ...
C-Y Hsieh, C-A Chen, S-F Chang, C-M Ho, T-Y Chu, M-H Chuang, Ho, CM; Cheng, WF; Chu, TY; Chen, CA; Chuang, MH; Chang, SF; Hsieh, CY, W-F Cheng   +7 more
core   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

Cytopathology, EarlyView.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source

Exfoliative cytology as a tool in the preinvasive anal lesions diagnosis

Medisur
The anal cancer increase in high-risk populations stimulates the implementation of protocols to carry out early diagnosis, as well as the monitoring of high-grade anal intraepithelial neoplasia as a precursor lesion.
Javier Martínez Navarro
doaj  

Histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center, Jimma, Southwest Ethiopia: A two-year cross-sectional study.

PLoS ONE
BackgroundThe cervix is the lower portion of the uterus, which connects this organ to the vagina through the endocervical canal.ObjectiveThis study aimed to determine the histopathologic patterns and factors associated with cervical lesions at Jimma ...
Birhanu Hailu Tirkaso, Tesfaye Hurgesa Bayisa, Tewodros Wubshet Desta   +2 more
doaj   +1 more source

RNA Extended Interventional Nucleic Acid (REINA) Longitudinal Study: Decreased Risk of CIN2+/CIN3+ With Low‐Grade Cytology After A Previous Negative HPV Test

Cytopathology, EarlyView.
REINA study shows decreased immediate and long‐term risks of CIN2+ and CIN3+ lesions in mRNA HPV‐positive women with minor cytological abnormalities after a previous negative Aptima HPV test in the first round. The decreased CIN2+/CIN3+ risks, below colposcopy referral thresholds, can modify women's management, highlighting the importance of ...
Rosario Granados, Joanny A. Duarte, David R. Luján, Ana M. Gutierrez‐Pecharromán, Isabel Solís, Lourdes Molpeceres, Paloma Bajo   +6 more
wiley   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

Patologia cervicale e nuove metodologie diagnostico terapeutiche [PDF]

, 2009
la cervice uterina è un distretto anatomico molto complesso, può essere sede di patologie infettive, preneoplastiche e neoplastiche. tra le patologie infettive, la più diffusa oggi è l' infezione da HPV diagnosticabile con svariati test in commercio e ...
Lavitola, Giada
core