Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello +10 more
wiley +1 more source
A Dual-Cuboid Constraint Method with Marching Cubes-Based Contour Extraction for Verticality Inspection of Square Tower Structures. [PDF]
Zhou M +8 more
europepmc +1 more source
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
High-Resolution CSRR-Based Microwave Sensor for Soil Moisture Content Monitoring. [PDF]
Alduwish S +4 more
europepmc +1 more source
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang +7 more
wiley +1 more source
Preliminary Assessment of Critical Thinking Among Fifth-Year Dental Students Using Temporomandibular Disorder Questions: A Cross-Sectional Study. [PDF]
Hassan AF +4 more
europepmc +1 more source
Diagnostic and Clinical Patterns of Newly Diagnosed ANCA-Associated Vasculitis Before and After the 6 February 2023 Kahramanmaraş Earthquakes: A Multicenter Retrospective Study from Affected Provinces. [PDF]
Zontul S +11 more
europepmc +1 more source
Rectangular Augmented Row-Column Designs Generated From Contractions. [PDF]
Piepho HP, Williams E.
europepmc +1 more source
Addendum: Sea level much higher than assumed in most coastal hazard assessments. [PDF]
Seeger K, Minderhoud PSJ.
europepmc +1 more source

