Results 41 to 50 of about 2,077,602 (266)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The “Campo” in Izola [PDF]

open access: yesUrbani Izziv, 2001
Transformation of the Lonka parking lot into a square adjacent is one of pending tasks of physical planning policies in Izola. Proposals for a public urban square on the site were prepared by four invited groups of experts.
Lučka Ažman Momirski
doaj  

Démocratie de la place publique : l’anatomie du mouvement Gezi

open access: yesSocio, 2014
The article presents an analysis of the Gezi Parc movement in 2013 and situates it in a more general and transversal reflexion on the new forms of contestation, ranging from arab spring to indignatos in Europe.
Nilüfer Göle
doaj   +1 more source

Парки и скверы Хельсинки как городская доминанта

open access: yesИскусство Евразии, 2020
Статья посвящена парковой архитектуре Хельсинки, где общая площадь парков и скверов составляет 30 процентов территории. Внимание автора сосредоточено на парках центральной части города: ландшафтных, прогулочных, ботанических, приморских, то есть ...
Михалкова, Татьяна Кирилловна
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Urbani obvodni javni prostor – reka kot razvojni generator : Urban riverside public space – river as the generator of development [PDF]

open access: yesGeodetski Vestnik, 2012
Odprti javni prostori imajo ključno vlogo v razpoznavnosti mest, kar zlasti velja za javne prostore, ki leže ob rekah. Zato so reke, ki tečejo skozi mesta, njihovo naravno bogastvo in hkrati velik razvojni potencial. So močan ekonomski razvojni generator
Artur Olaj   +2 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Distribuição Espacial e Cobertura de Vegetação das Tipologias de Áreas Verdes de Curitiba, PR

open access: yesFloresta e Ambiente
RESUMO A vegetação nas cidades desempenha funções ecológicas, estéticas e sociais que melhoram a qualidade de vida urbana. Para que essas funções sejam eficientes é necessário a realização de estudos quantitativos e qualitativos das áreas verdes (AVs) na
Mayssa Mascarenhas Grise   +2 more
doaj   +1 more source

Smallest Squared Squares

open access: yes, 2013
In this paper we have a look at squared squares with small integer sidelengths, where the only restriction is that any two subsquares of the same size are not allowed to share a full border. We prove that there are exactly two such squared squares (and their mirrored versions) up to and including size 17x17. They are shown in Figure 1 (page 2).
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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