Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Poisson Counts, Square Root Transformation and Small Area Estimation: Square Root Transformation. [PDF]
Ghosh M, Ghosh T, Hirose MY.
europepmc +1 more source
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
A structure-preserving doubling algorithm for the square root of regular M-matrix
The matrix square root is widely encountered in many fields of mathematics. In this paper, based on the properties of M-matrix and quadratic matrix equations, we study the square root of M-matrix, and prove that for a regular M-matrix there always exists
Zehua Wang, Jinrui Guan, Ahmed Zubair
doaj +1 more source
Exact solution of the 1D Dirac equation for a pseudoscalar interaction potential with the inverse-square-root variation law. [PDF]
Ishkhanyan AM, Krainov VP.
europepmc +1 more source
Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Square Root Convexity of Fisher Information along Heat Flow in Dimension Two. [PDF]
Liu J, Gao X.
europepmc +1 more source
Wind Speed Distribution Direct Approximation by Accumulative Statistics of Measurements and Root-Mean-Square Deviation Control [PDF]
Vadim Romanuke
openalex +1 more source
Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source

