Results 111 to 120 of about 50,244 (265)

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

A Ceramic Network for Hybrid Solid Electrolyte Lithium Metal Batteries

Advanced Science, EarlyView.
An in‐plane aligned Ta‐LLZO ceramic network exhibits superior performance compared to conventional fillers, including single ceramic fibers and particles. The tortuosity within the polymeric phase of hybrid solid electrolytes is identified as a key parameter governing lithium‐ion transport pathways and dendrite suppression.
Luca Weckelmann, Jeong Seop Yoon, Jehad Ahmed, Krzysztof Dzieciol, Anna Windmüller, Luc Raijmakers, Sanja Tepavcevic, Hans Kungl, Venkat Srinivasan, Chih‐Long Tsai, Rüdiger‐A. Eichel   +10 more
wiley   +1 more source

Confirmation of bean leaf beetle, Cerotoma trifurcata, feeding on cucurbits

Journal of Insect Science, 2004
The objective of these studies was to assess the degree to which bean leaf beetle, Cerotoma trifurcata (Forster), will feed on cucurbits. In 2003, we documented an infestation of C. trifurcata in a commercial pumpkin field near Rosemount, MN, USA.
R.L. Koch, E.C. Burkness, W.D. Hutchison
doaj  

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

Advanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang, Yiwei Wang, Bing Zheng, Liu Yang, Jingyi Yue, Qian Zhou, Jinrong Huang, Yongyun Mao, Qian Li, Jifei Wang, Dongsheng Tang, Yuxin Tang, Bingpu Zhou, Bing Ji   +13 more
wiley   +1 more source

Multi‐Stimuli Responsive Viologen‐Crosslinked Eutectogels Derived From Natural Deep Eutectic Solvents for Information Security and Motion Detection

Advanced Science, EarlyView.
Described herein is the development of an organic eutectic gel based on a deep eutectic mixture of naturally derived betaine and lactic acid. The eutectic gels exhibit reversible color‐switching in response to multiple stimuli including strain, UV light, and temperature, enabling advanced applications in information security, intelligent wearable ...
Zhiang Bai, Wai Lean Koay, Xin Yi Oh, Vinh Xuan Truong   +3 more
wiley   +1 more source

ZrO2 Aerogel‐Supported Pd Nanoparticles for Photothermal CO2 Reduction

Advanced Science, EarlyView.
Nanoparticle‐based aerogels are promising catalysts for photothermal reactions due to optical transparency, high surface area, and low thermal conductivity. Here, we present deposition of Pd nanoparticles on ZrO2 aerogel granules by a wet‐impregnation approach.
David Kiwic, Linard Räz, Elena Tervoort, Markus Niederberger   +3 more
wiley   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Chitosan-loaded copper oxide nanocomposite as a promising antiviral alleviates Zucchini yellow mosaic virus infection in squash plants. [PDF]

BMC Plant Biol
Ahmed EA, Shaaban A, Hemida KA, Rady MM, Ali AI, Farrag AA.   +5 more
europepmc   +1 more source