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Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005The scavenger receptor class B, type I (SR-BI) mediates the cellular selective uptake of cholesteryl esters and other lipids from high-density lipoproteins (HDL) and low-density lipoproteins (LDL). This process, unlike classical receptor-mediated endocytosis, does not result in lipoprotein degradation. Instead, the lipid depleted particles are released
Marcelo Ehrlich +3 more
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Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL
Journal of Molecular Medicine, 2006The concentration, composition, shape, and size of plasma high-density lipoprotein (HDL) are determined by numerous proteins that influence its biogenesis, remodeling, and catabolism. The discoveries of the HDL receptor (scavenger receptor class B type I, SR-BI) and the ABCA1 (ATP-binding cassette transporter A1) lipid transporter provided two missing ...
Monty Krieger +3 more
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Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
Science, 1996S. Acton +5 more
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SR-BI-mediated HDL cholesteryl ester delivery in the adrenal gland
Molecular and Cellular Endocrinology, 2009In adrenocortical cells, scavenger receptor class B, type I (SR-BI) is localized in specialized plasma membrane compartments, called microvillar channels, that retain high density lipoprotein particles (HDL) and are sites for the selective uptake of cholesteryl esters (CE).
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Interaction of serum apolipoproteins with scavenger receptor (SR)-BI
Atherosclerosis, 2000Michael C. Phillips +2 more
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Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36
Nature, 2013D. Neculai +14 more
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