Scale reliant mixed effects models enhance microbiome data analysis. [PDF]
MicrobiomeMcGovern KC, Silverman JD.
europepmc +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Strontium and gallium doping enhances <i>in vivo</i> bone regeneration in biomimetic hydroxyapatite 3D-printed scaffolds. [PDF]
Mater Today BioLodoso-Torrecilla I +10 more
europepmc +1 more source
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Structured template for standardised reporting of non-contrast computed tomography in urinary stone disease as a superior tool for urologists - a randomised controlled trial. [PDF]
BMC UrolGlienke M +9 more
europepmc +1 more source
Advanced Science, EarlyView.Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy +4 more
wiley +1 more source
Multiple pathways of institutional environment driving the reduction of veterinary antibiotic overuse: Evidence from dairy farmers in Heilongjiang Province, China. [PDF]
One HealthJiang B, Li M, Bai H.
europepmc +1 more source
Advanced Science, EarlyView.The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo +6 more
wiley +1 more source
Osteogenic and Anti-Inflammatory Effects of Strontium-Loaded Polydopamine on Micro-Arc Oxidized Titanium Surfaces. [PDF]
J Funct BiomaterYang Y +6 more
europepmc +1 more source