Results 301 to 310 of about 512,141 (378)

Isolation, Characterization, and Wound‐Healing Potential of β‐D‐Glucan from Lycoperdon pyriforme Schaeff

ChemistryOpen, EarlyView.
Mushrooms have become a prominent focus in alternative medicine and are now the subject of increasingly detailed scientific investigation. This study explores the isolation, purification, and characterization of β‐D‐glucan from Lycoperdon pyriforme, with particular emphasis on its wound‐healing potential. The aim of this research is to isolate, purify,
Elif Yavuz‐Dokgöz, Meltem Güleç, Burçin İzbudak, Onur Şahin, Ayça Bal‐Öztürk   +4 more
wiley   +1 more source

Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of an anti-PD-1 antibody. [PDF]

Front Pharmacol
Li JX, Tan SY, Li LQ, Zheng YH, Zhao L, Zhu HR, He HL, Zhang YY, Li RZ, Bao TY, Zhang YZ, Yang XM, Zhang H, Chen HH, Wu BW, Lin X, Lin XS, Lin YC, Sui XB, Xie Y, Zhou XM, Yan PY.   +21 more
europepmc   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Thiostrepton Suppresses the Progression of Rhabdomyosarcoma by Inhibiting the PI3K‐AKT Signaling Pathway

Pediatric Discovery, EarlyView.
The study establish TST as a multi‐mechanism PI3K‐AKT inhibitor for refractory RMS while validating Cmap‐driven drug repurposing for pediatric oncology. ABSTRACT Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma with 5‐year survival below 30% in high‐risk/metastatic cases, was investigated through integrated bioinformatics analysis (
Yu Wang, Peng Hong, Zhiqiang Gao, Wei Ma, Zaihong Hu, Jie Lin, Kongkong Cui, Qinlin Shi, Xiao‐Mao Tian, Guanghui Wei   +9 more
wiley   +1 more source

ARRDC3 tyrosine phosphorylation functions as a switch to control c-Src versus WWP2 interactions and distinct scaffolding functions. [PDF]

J Biol Chem
Caplan M, Bardeleben C, Dhawan K, Plawat R, Kufareva I, Trejo J.   +5 more
europepmc   +1 more source

Vinculin phosphorylation by the src kinase. Interaction of vinculin with phospholipid vesicles.

, 1983
Seiji Ito, D K Werth, Nancy Richert, Ira Pastan   +3 more
openalex   +1 more source

Rheological and tribological behavior of new 3D‐printed poly(lactic acid) modified by ionic liquid

Polymer International, EarlyView.
Addition of the ionic liquid reduces surface roughness and coefficient of friction, shifting the transition from running‐in to steady state from around 10 m to over 60 m when sliding in the direction parallel to layer orientation and over 70 m for sliding perpendicular to it. Abstract Poly(lactic acid) (PLA) modified by addition of the ionic liquid (IL)
Cristian Sánchez‐Rodríguez, Ramón Pamies, José Sanes, Francisco José Carrión‐Vilches, María Dolores Bermúdez, Marta Doval‐Miñarro   +5 more
wiley   +1 more source

Acquisition of transforming properties by FYN, a normal SRC-related human gene.

, 1988
Toshiaki Kawakami, Yuko Kawakami, S A Aaronson, Keith C. Robbins   +3 more
openalex   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source