Results 161 to 170 of about 40,020 (266)

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales   +4 more
wiley   +1 more source

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

open access: yesThe FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi   +6 more
wiley   +1 more source

What Drives Banks' and FinTechs' Systemic Risk: An Analysis on Crypto Assets Contagion and Firm‐Specific Characteristics

open access: yesFinancial Markets, Institutions &Instruments, EarlyView.
ABSTRACT This paper studies the determinants of banks' and fintech companies' systemic risk. We adopt both a systemic and firm‐level perspective and consider not only factors traditionally used to explain systemic riskiness, which have never been applied to the fintech sector, but also the new potential source of instability, for both banks and fintech
Domenico Curcio   +3 more
wiley   +1 more source

Development of CCMb: A Low‐Mg Calcite Reference Material for In Situ Measurement of δ18O, δ13C and Selected Trace Elements

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points Low‐Mg calcite RM developed for in situ microanalysis applications in palaeoclimatology (δ18O, δ13C; Mg, Sr m/m). New data for calcite CRM IAEA‐603 (δ18O, δ13C by SIMS and GS‐IRMS; Mg m/m). No detectable IMF effect of Mg on SIMS δ18O determinations for mass fractions < 3650 μg g‐1.
Andreas T. Hertwig   +13 more
wiley   +1 more source

Restoring access to long-term social recognition memories disrupted by sleep deprivation. [PDF]

open access: yesSci Adv
Sarma A   +12 more
europepmc   +1 more source

Assessment and Correction of Non‐Linearity Effects for In Situ Rb‐Sr Geochronology Applied to High 87Rb/86Sr Mica

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points Measurement of 86Sr at count rates < 1500 cps can result in statistical bias. Non‐linear signals in analogue detection mode (e.g., Rb) present a challenge for accurately dating high 87Rb/86Sr mica (> 1000). Accounting for these considerations, high 87Rb/86Sr mica are dated here with accuracies of ∼ 1%.
Duane C. Petts   +5 more
wiley   +1 more source

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