Results 111 to 120 of about 31,142 (277)

Ultra-broadband wavelength-swept Tm-doped fiber laser using wavelength-combined gain stages [PDF]

, 2015
A wavelength-swept thulium-doped fiber laser system employing two parallel cavities with two different fiber gain stages is reported. The fiber gain stages were tailored to provide emission in complementary bands with external wavelength-dependent ...
Agger, C. S. Chenug, Chinn, Clarkson, Ehrenreich, Geng, H. Liang, J. M. O. Daniel, Liang, M. Tokurakawa, Moulton, Oh, Shen, Tokurakawa, W. A. Clarkson, Yun   +15 more
core   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch

, 2019
Polarization dependent image artifacts are common in optical coherence tomography imaging. Polarization insensitive detection scheme for swept source based optical coherence tomography systems is well established but is yet to be demonstrated for all ...
Otuya, D., Sharma, G., Singh, K., Tearney, G.   +3 more
core   +1 more source

Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments [PDF]

, 2005
(SS-OCT) system, which uses a ready-to-ship scanning lightsource, is demonstrated. The light source has a center wavelength of 1.31μm, -3 dB wavelength range of 110 nm, scanning rate of 20 KHz, and highlinearity in frequency scanning. This paper presents
Akiba Masahiro, Chan Kin-Pui, Chong Changho, Itoh Masahide, Madjarova Violeta Dimitrova, Makita Shuichi, Morosawa Atsushi, Sakai Toru, Yasuno Yoshiaki, Yatagai Toyohiko, 伊藤 雅英, 安野 嘉晃   +11 more
core   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Novel Insight into Morphological Features and Vascular Profile of Selected Macular Dystrophies Using Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography [PDF]

, 2018
Our perception of macular dystrophies has evolved overtime from collective grouping into hereditary disorders of unclear etiology and no effective treatment to avid search for the underlying pathogenic mechanism that would provide base for future therapy.
Leila, Mahmoud, Moussa, Magdy
core   +2 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Non-Destructive Inspection Methods for LEDs Using Real-Time Displaying Optical Coherence Tomography

Sensors, 2012
In this study, we report the applicability of two different Optical Coherence Tomography (OCT) technologies for inspecting Light Emitting Diode (LED) structures.
Suhwan Kim, Jeehyun Kim, Unsang Jung, Nam Hyun Cho   +3 more
doaj   +1 more source

Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation [PDF]

, 2008
We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a frequency swept laser centered at 1.31 μm with a scanning rate of 20 kHz.
Makita Shuichi, Yamanari Masahiro, Yasuno Yoshiaki, 安野 嘉晃   +3 more
core   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source