Results 91 to 100 of about 35,631 (247)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Cost‐Effectiveness of Venom Immunotherapy in Preventing Severe Bee and Wasp Sting Reactions

Allergy, EarlyView.
This study evaluates the cost‐effectiveness of Hymenoptera venom depot immunotherapy (HVDI) with Alutard SQ compared to adrenaline auto‐injectors (AAIs) in Denmark. The model incorporates both psychological and physiological benefits to estimate quality‐adjusted life years (QALYs).
Gunter Sturm, Maria Beatrice Bilò, Carmen Vidal, Joanna N.G. Oude Elberink, Jochen Schmitt, Andreas Kallsoy Slættanes, Thilo Jakob   +6 more
wiley   +1 more source

Development of a nomogram for sperm retrieval at microTESE for idiopathic non‐obstructive azoospermia in a multi‐center cohort study

Andrology, EarlyView.
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Giorgio Ivan Russo, Edoardo Pozzi, Fausto Negri, Marco Falcone, Emanuele Zupo, Mirko Preto, Maria Giovanna Asmundo, Sandrine Chamayou, Murat Dursun, Ateş Kadıoğlu, Andrea Salonia   +10 more
wiley   +1 more source

Dynamic 16S rRNA Sequencing of the Abdominal Wall Surgical Site Highlights Potential Pathways of Incisional Surgical Site Infection in Colorectal Surgery

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Understanding the microbial changes within the surgical site may enhance our understanding of the origin and subsequent role of microbes in the causation of incisional surgical site infections (SSIs). In this study we used 16S rRNA sequencing to establish the dynamic microbiota of the surgical site in patients undergoing bowel ...
Veral Vishnoi, Emily C. Hoedt, Matthew Watson, Madelyn Gramlick, Michelle Zhao, Natalie Lott, Rosemary Carroll, Peter Pockney, Stephen R. Smith, Simon Keely   +9 more
wiley   +1 more source

16S rRNA Amplicon Sequencing of the Intraoperative Surgical Site Demonstrates an Aberrant Microbiota Which Can Predict Colorectal Surgical Site Infection

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Surgical Site Infection (SSI) of an abdominal incision is a dreaded infectious complication following colorectal surgery. Understanding the intraoperative microbiology holds the key to prevention. Genomic sequencing has revolutionised culture‐independent techniques, allowing for a more sensitive tool in microbial detection.
Veral Vishnoi, Emily C. Hoedt, Michelle Zhao, Rosemary Carroll, Shaveen Kanakaratne, Natalie Lott, Peter Pockney, Stephen R. Smith, Simon Keely   +8 more
wiley   +1 more source

Pigment-based biosensors for environmental monitoring

Talanta Open
Environmental pollution is progressively escalating owing to an increase in population and industrialization. Various industrial wastes are discharged into the water, soil, and air.
Shivangini Desai, Sonal Desai
doaj   +1 more source

Using sleep to enhance exposure treatment for anxious children: A pilot study

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar, Ronald M. Rapee, Cassie H. Lavell, Allison G. Harvey, Thomas H. Ollendick   +4 more
wiley   +1 more source

Self‐criticism and dependency in adolescents with depression: Associations with clinical features and psychological functioning

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives The personality dimensions of self‐criticism and dependency have been shown to confer vulnerability to depression, and psychopathology more broadly, in adults. However, evidence for the roles of these personality dimensions in young people is weaker, particularly because most studies in this area have been conducted in non‐clinical ...
Yushi Bai, Nick Midgley, Patrick Luyten
wiley   +1 more source

Assessing the Progress of Stock Rebuilding in the Northeast Atlantic Against Levels That Can Produce Maximum Sustainable Yield

Fish and Fisheries, EarlyView.
ABSTRACT Rebuilding fish stocks to levels above which they produce Maximum Sustainable Yield (MSY) is a management aim for all European commercially exploited stocks. Progress is typically monitored against the fishing mortality that produces MSY in the long term (FMSY), however, the corresponding biomass target (BMSY) is rarely evaluated nor reported.
Henning Winker, Massimiliano Cardinale, Rishi Sharma, Laurence T. Kell, Iago Mosqueira, Christopher Griffiths   +5 more
wiley   +1 more source

Global Analysis of Shallow Underwater Fish Observation Research: 70 Years of Progress, Persistent Geographic Biases and a Path Forward

Fish and Fisheries, EarlyView.
ABSTRACT Marine ecosystems are increasingly threatened by overfishing, pollution, coastal development and climate change, underscoring the need for long‐term, representative information on key fish populations and habitats to inform management and policy.
Angus John van Wyk, Rick D. Stuart‐Smith, Jordan S. Goetze, Eva Maire, Elodie Heyns‐Veale, Kaylee Smit, Tim J. Langlois, M. Aaron MacNeil, Alejandro Pérez‐Matus, Amanda T. Lombard, Ana Carolina, Christy Semmens, Ella Clausius, Fernanda A. Rolim, Jonathan S. Lefcheck, Jacquomo Monk, Joanna K. Schmid, Katherine Tattersall, Laura Ghigliotti, Luther Adams, Melita Samoilys, Pascale Chabanet, Paul Whomersley, Peter Walsh, Reiji Masuda, Russell Brainard, Anthony Bernard   +26 more
wiley   +1 more source