Results 31 to 40 of about 5,569 (140)

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

Allergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson, Maciej Kupczyk, Barbro Dahlén, Kenji Izuhara, Mina Gaga, Nikos M. Siafakas, Alberto Papi, Bianca Beghe, Guy Joos, Klaus F. Rabe, Elisabeth H. Bel, Sebastian L. Johnston, Pascal Chanez, Mark Gjomarkaj, Peter H. Howarth, Ewa Niżankowska‐Mogilnicka, Roelinde Middelveld, Sven‐Erik Dahlén, Apostolos Bossios, Anna James, on behalf of the BIOAIR (Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease) and ChAMP consortia   +20 more
wiley   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Functional exercise capacity and health-related quality of life in people with asbestos related pleural disease: an observational study

BMC Pulmonary Medicine, 2013
Background Functional exercise capacity in people with asbestos related pleural disease (ARPD) is unknown and there are no data on health-related quality of life (HRQoL).
Dale Marita T, McKeough Zoe J, Munoz Phillip A, Corte Peter, Bye Peter TP, Alison Jennifer A   +5 more
doaj   +1 more source

Asthma and Multimorbidity Amongst Ethnic Minority Groups in High Income Countries

Clinical &Experimental Allergy, EarlyView.
There is a tight intersection between asthma, deprivation, ethnicity, multimorbidity and poor clinical outcomes. An integrated, holistic and culturally tailored approach is needed to improve clinical outcomes amongst ethnic minority groups with asthma and multimorbidity. ABSTRACT Asthma is one of the commonest noncommunicable diseases worldwide.
Mamidipudi Thirumala Krishna, Saibal Moitra, Anna Freeman, Ben Ainsworth, Rebecca Knibb, Ramesh Kurukulaaratchy, Adel H. Mansur   +6 more
wiley   +1 more source

Efficacy of pulmonary rehabilitation combined with minimal-dose adjunctive TCM (Shen Yi Capsules and Hua Chan Su) in improving postoperative outcomes for non-small cell lung cancer: a randomized controlled trial

Frontiers in Medicine
BackgroundInterstitial lung disease (ILD) is a chronic respiratory disease that is characterized by progressive pulmonary fibrosis, impaired gas exchange, and reduced exercise tolerance.ObjectiveThe present investigation aimed to evaluate the efficacy of
Ge Chunyan, Wang Fengshuang, Li Mei, Chen Zhiqun, Han Dongmei   +4 more
doaj   +1 more source

A Real‐World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Among patients with severe eosinophilic asthma, benralizumab was associated with greater improvements in asthma outcomes—such as improved asthma control, quality of life and remission rates—compared to biologic‐naïve patients. ABSTRACT Background Real‐world data on benralizumab in patients with severe eosinophilic asthma–while controlling for ...
Dennis Thomas, Vanessa M. McDonald, Gijo Thomas, Joy Lee, Li Ping Chung, Matthew Peters, Shakti D. Shukla, Yuto Hamada, Erin S. Harvey, Michael Fricker, Hayley See, Rejoy Sabin Thomas, Claude S. Farah, Andrew Gillman, Constance H. Katelaris, Gregory P. Katsoulotos, David Langton, Peter G. Middleton, Paul Reynolds, Janet Rimmer, Francis Thien, Stephen Vincent, John W. Upham, Peter G. Gibson   +23 more
wiley   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

Clinical &Experimental Allergy, EarlyView.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos, Chen‐Yuan Chiang, M. Innes Asher, Guy B. Marks, Asma El Sony, Refiloe Masekela, Karen Bissell, Eamon Ellwood, Philippa Ellwood, Neil Pearce, David P. Strachan, A. Elena Martínez‐Torres, Manuel Sánchez‐Solís, Kevin Mortimer, Eva Morales, The Global Asthma Network Phase I Study Group   +15 more
wiley   +1 more source

Cytopathology Terminology Systems: European Federation of Cytological Societies Survey on Practice in Europe

Cytopathology, EarlyView.
Cytology terminologies are widely accepted within Europe based on EFCS survey. The Bethesda System for reporting cervical cytology and the Bethesda System for reporting thyroid cytopathology have been implemented by most of the responding countries. ABSTRACT Cytopathologists communicate with clinicians via cytopathology reports.
Ivana Kholová, Colleen Vrbin, Esther Diana Rossi, David Poller, Pinar Firat, Sevgen Onder, Beatrix Cochand‐Priollet, Henrik Griesser, Guido Fadda, Marianne Engels, Massimo Bongiovanni, Pio Zeppa, Ashish Chandra, Ambrogio Fassina, Philippe Vielh, Danijela Vrdoljak‐Mozetic, European Federation of Cytological Societies National Representatives, Shaira Sahebali, Pawel Gajdzis, Christina Kåbjörn Gustafsson, Monique Courtade‐Saidi, Maria Nasioutziki, Filipa Moreno, Robby Kibbelaar, Jaroslava Dušková, Wolfgang Pokieser, Margareta Strojan Fležar, Maria D. Lozano, Oksana Sulaieva, Pavlina Botsiun, Laszlo Vass, Ljube Ivkovski, Tibor Mezei, Nina Juric, Mikk Abram, Cornelia Amalinei, Milana Panjkovic, Dalius Baltusnikas, Aleksandrina Vlahova, Rene Gerhard, Cioly Rivero‐Colmenarez, Ljiljana Vučković, Fatlinda Sadiku, Giovanni Negri, Erion Sukaj, Jurate Asmundsson, Lucia Krivošíková   +46 more
wiley   +1 more source

The Association of Sarcopenic Obesity With Respiratory Function Outcomes in Adults: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Sarcopenic obesity has been associated with various health conditions and mortality. Our objective was to systematically review and estimate the association between sarcopenic obesity and respiratory function outcomes. We searched EMBASE, MEDLINE, and Google Scholar for observational studies involving adults (≥ 18 years), defined sarcopenic ...
Tasneem Baabbad, Magaly Aceves‐Martins, Graham Horgan, Phyo Kyaw Myint, Baukje de Roos   +4 more
wiley   +1 more source

The efficacy of -acetylcysteine in chronic obstructive pulmonary disease patients: a meta-analysis

Therapeutic Advances in Respiratory Disease, 2023
Background: N -acetylcysteine (NAC) may reduce acute exacerbations of chronic obstructive pulmonary disease through an antioxidant effect. Due to the heterogeneity in studies, the currently available data do not confirm the efficacy of oral NAC therapy ...
Chienhsiu Huang, Sufang Kuo, Lichen Lin, Yalun Yang   +3 more
doaj   +1 more source