Results 121 to 130 of about 78,533 (262)

Determinants of cardiorespiratory fitness after successfully reperfused ST-elevation myocardial infarction. [PDF]

Curr Probl Cardiol
Hogwood AC, Smarż K, Golino M, Tysarowski M, Canada JM, Zaborska B, Dziekan-Wisławska K, Zioło J, West JD, Jaxa-Chamiec T, Kontos E, Barron AM, Mbualungu J, Marchetta M, Lopez R, Moroni F, Arena R, Tassell BV, Abbate A.   +18 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Beyond atherosclerosis: polycythemia vera presenting as ST-elevation myocardial infarction-a case report. [PDF]

Eur Heart J Case Rep
Panda A, Kumar S, Mishra SS.
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Left ventricular thrombus in Takotsubo syndrome and ST-elevation myocardial infarction. [PDF]

Open Heart
Jha S, Simonsson M, Poller A, Molander L, Thorleifsson S, Pirazzi C, Bentzel S, Torild P, Andersson EA, Shekka Espinosa A, Sevastianova V, Salahuddin S, Zeijlon R, Elmahdy A, Skoglund K, Omerovic E, Redfors B.   +16 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

R-on-T-triggered ventricular fibrillation during acute anterior ST-elevation myocardial infarction. [PDF]

Eur Heart J Case Rep
Savaş G, Nural A, Yazıcı S, Terzi S.
europepmc   +1 more source

Clinical characteristics and in‐hospital mortality among insulin pump users with acute coronary syndrome in the predominantly open‐loop era: A UK‐wide MINAP registry analysis

Diabetic Medicine, EarlyView.
Abstract Background We compared characteristics of adults with insulin‐treated diabetes using continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) during admission with acute coronary syndrome (ACS) and identified factors associated with in‐hospital mortality among CSII users.
Harshal Deshmukh, Moosa Shaikh, Emma G. Wilmot, Eric Kilpatrick, Sudipta Chattopadhyay, Thozhukat Sathyapalan, Joseph John   +6 more
wiley   +1 more source

Clinical and Angiographic Predictors of No-Reflow and Its Impact on Outcomes in ST-Elevation Myocardial Infarction: A Retrospective Study. [PDF]

Clin Cardiol
Bashir H, Berkha FNU, Malik J, Perveen A.   +3 more
europepmc   +1 more source