Results 161 to 170 of about 163,674 (312)

ST segment elevation in a patient presenting with renal colic pain

Saudi Journal of Kidney Diseases and Transplantation, 2011
ST segment elevation of more than 1 mm from the baseline is an electrocardiographic presentation of acute myocardial injury. This phenomenon is not confined only to ischemic injury, and various other etiological factors have been described in relation to
Zohair Al Aseri, Owais M Suriya, Hossam A Hassan   +2 more
doaj  

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Correaltion of Thrombolysis in Myocardial Infarction Risk Score and Angiographic Score in Patients with ST-Elevation in Myocardial Infarction

مجله دانشکده پزشکی اصفهان, 2009
Background: Myocardial Infarction is a common and lethal disease, especially in first hours. Rapid and correct decision is essential for priority of advance therapies and this study follows the accuracy of a scoring system for this triage.
Mohammadreza Akhbari, Hamid Sanei, Masoume Sadeghi, Mojtaba Akbari, Nahid Sistan, Iraj Jafaripour, Mehradad Rashidi Benam, Nafishe Motamedi   +7 more
doaj  

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

老年人急性冠脉综合征患者肌钙蛋白测定的临床价值

Zhongguo shiyan zhenduanxue, 2011
急性冠脉综合征（acute coronary syndrome,ACS）是一组综合病征包括了不稳定型心绞痛（unstable angiona,UA）,非ST段抬高型心肌梗死（non-ST-segment elevation myocardial infarction,NSTEMI）和ST段抬高型心肌梗死（ST-segment elevation myocardial infarction,STEMI）。它们有共同的病理基础 ...
许靖, 段堂堂
doaj  

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Fatal Pembrolizumab‐Induced Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis in a Patient With Advanced Lung Adenocarcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
Po‐Chih Chang, Ting‐Wei Chang, Chia‐Yu Kuo, Yi‐Zhe Wu   +3 more
wiley   +1 more source

Targeting inflammation in cardiometabolic disease: Icosapent ethyl modulates monocyte‐derived macrophages isolated from patients with cardiovascular disease with or without type 2 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward, M. U. Shah, K. Lee, P. E. Squires, C. E. Hills   +4 more
wiley   +1 more source

Intracoronary adjunctive therapies for ST-elevation myocardial infarction: a network meta-analysis of trials. [PDF]

Eur Heart J Cardiovasc Pharmacother
Laborante R, Bianchini E, Ciliberti G, Paglianiti DA, Filomia S, Bianchini F, Galli M, Biondi-Zoccai G, Serruys PW, Crea F, Patti G, Savarese G, Trani C, Burzotta F, D'Amario D.   +14 more
europepmc   +1 more source