Results 191 to 200 of about 155,647 (305)

The efficacy of preoperative evolocumab-rosuvastatin combination therapy in patients with ST-elevation myocardial infarction. [PDF]

PLoS One
Li H, Dong H, Bao S, Wang X, Fu Z.
europepmc   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Coronary Artery Bypass Grafting Following ST Elevation Myocardial Infarction Outcomes Are Associated with Time to Surgery. [PDF]

Interdiscip Cardiovasc Thorac Surg
Crane JG, Trivedi J, Endo T, Lytle IR, Pahwa S, Vaidya Y, Slaughter MS, Gallo M.   +7 more
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Achieving door-to-balloon time ≤ 90 minutes in ST-elevation myocardial infarction: a retrospective clinical audit from a tertiary care centre in India. [PDF]

Int J Emerg Med
Krishnan R, Dhileeban CM, Hariprasad S, Umer PA, Balaji S, Kavitha B.   +5 more
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

Acute ST-Elevation Myocardial Infarction (STEMI) Diagnoses in a Biventricular-Paced ECG. [PDF]

Cureus
Govil D, Affas ZR, Nicholson C, Bradley C, Zughaib M.   +4 more
europepmc   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source

Feasibility and effectiveness of distal radial access in ST-elevation myocardial infarction from a SPEEDY PCI subanalysis. [PDF]

Sci Rep
Takahashi A, Torii S, Ono Y, Taniwaki M, Oguri M, Teramura M, Kato R, Otsuki S, Suzuki H, Yoshimachi F, Ueda H, Shioji K, Nakazawa G, Sakurai K, Tsujimoto M, Ando M, Kozai T, Aoyama R, Ikari Y.   +18 more
europepmc   +1 more source