Results 191 to 200 of about 78,533 (262)

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, Volume 36, Issue 5, September 2026.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Relationship between body mass index and endogenous fibrinolytic status in 600 patients with ST-elevation myocardial infarction. [PDF]

Cardiovasc Res
Leader JH, Vilahur G, Ajjan RA, Kanji R, Gue YX, Farag M, Gorog DA.   +6 more
europepmc   +1 more source

Impact of Simultaneous Initiation of Finerenone and Empagliflozin on Albuminuria Irrespective of Baseline HbA1c Levels: A Participant‐Level Exploratory Analysis of the Randomised CONFIDENCE Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7964-7973, September 2026.
ABSTRACT Aims This prespecified analysis evaluated whether the safety and efficacy of finerenone and a sodium–glucose cotransporter 2 inhibitor (SGLT2i) combination vary by baseline glycated haemoglobin (HbA1c). Materials and Methods Adults with type 2 diabetes and a urinary albumin‐to‐creatinine ratio (UACR) of 100 − < 5000 mg/g, estimated glomerular ...
Janet B. McGill, Jennifer B. Green, Hiddo J. L. Heerspink, Johannes F. E. Mann, Amy K. Mottl, Julio Rosenstock, Peter Rossing, Muthiah Vaduganathan, Masaomi Nangaku, Meike Brinker, Charlie Scott, Katja Rohwedder, Li Li, Na Li, Margarida Seco, Rajiv Agarwal   +15 more
wiley   +1 more source

Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction. [PDF]

World J Cardiol
Milaras N, Toutouzas K, Sideris S.
europepmc   +1 more source

Anti‐inflammatory agents in atherosclerosis—and a need for reform: Extraordinary claims require extraordinary evidence

Journal of Internal Medicine, Volume 300, Issue 3, Page 258-283, September 2026.
Abstract Since 1858, human atherosclerotic plaques have been shown to contain immune cells. But are these cells suitable therapeutic targets? Dozens of clinical trials of anti‐inflammatory agents other than colchicine have been performed in patients with clinically evident atherosclerosis.
Kevin Jon Williams
wiley   +1 more source

Concurrent Diabetic Ketoacidosis and Non-ST-Elevation Myocardial Infarction: A Complex Cardiometabolic Emergency. [PDF]

Cureus
Moin K, Amini Z, Umar R.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, Volume 16, Issue 8, Page 1550-1562, August 2026.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Assessment of the Effectiveness of Early Versus Delayed Invasive Strategies in Non-ST Elevation Myocardial Infarction (NSTEMI): A Systematic Review and Meta-Analysis. [PDF]

Cureus
Kamble A, Revunuru NR, Rangachari B, Bharat Patel V, Ullah I, Ahmed Z.   +5 more
europepmc   +1 more source

Do or Die: A Rapid‐Fire Tabletop Review of “Must Know” Emergency Medicine Pathologies

AEM Education and Training, Volume 10, Issue 4, August 2026.
ABSTRACT Background Emergency medicine (EM) physicians must rapidly recognize and manage time‐critical conditions; however, standardized methods to teach and assess competency in these scenarios remain limited and resource‐intensive. Objective To develop and implement a low‐resource, standardized tabletop simulation to evaluate EM residents' ability to
Jennifer Yee, Colin G. Kaide, Geremiha Emerson, Kelsey H. Jordan, Sorabh Khandelwal   +4 more
wiley   +1 more source

Radiation-Associated Calcific Right Coronary Artery Occlusion Presenting as ST-Elevation Myocardial Infarction: Emphasizing the Need for Early Cardiovascular Screening. [PDF]

Cureus
Bani Yaseen K, Lataifeh H, Abouzeid W, Haddad AW, Mirza N.   +4 more
europepmc   +1 more source