Results 241 to 250 of about 3,076,940 (300)

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Exosomal let‐7c‐5p From AMI Patient Plasma Modulates Neuronal PANoptosis via ZBP1 In Vitro

open access: yesCell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Acute myocardial infarction (AMI) significantly elevates the risk of ischemic stroke (IS), yet the molecular mechanisms linking cardiac and cerebral injury remain unclear. Emerging evidence highlights the role of circulating exosomes in mediating inter‐organ communication via microRNAs (miRNAs). In this study, plasma exosomes from AMI patients
Zhiyong Zhang   +11 more
wiley   +1 more source

Angiographic characteristics of older patients with non-ST elevation myocardial infarction undergoing invasive strategy: A pre-specified analysis from the SENIOR-RITA trial. [PDF]

open access: yesEur Heart J Open
Pompei G   +22 more
europepmc   +1 more source

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