Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Reactive astrocyte-derived neurotoxicity is mitigated by vitronectin in traumatic brain injury mouse model. [PDF]
Yamashita M +6 more
europepmc +1 more source
Inspired by nature's competitive maneuvers, this study introduces a combustion‐driven soft actuator that powers a multi‐modal “Jump‐and‐Fly Catbot” (JFC). With millisecond response, high‐force output (over 70 times its weight) and precise control (error within 5%), the robot can jump, fly, hover, and escape from challenging environments, achieving ...
Hongkuan Ma +4 more
wiley +1 more source
Postoperative Left Anterior Descending Artery Compression and Left Ventricular Thrombus Following the Repair of a Penetrating Right Ventricular Injury in an Adolescent: A Case Report. [PDF]
O'Donnell R, Chung J, Jogia P.
europepmc +1 more source
812 Development of evaluation equipment for stab resistance of clothes
Tomohiro Bingo +2 more
openalex +1 more source
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding +11 more
wiley +1 more source
Multidisciplinary Rescue Airway Management in a Self-Inflicted Penetrating Neck Injury: A Case Report. [PDF]
Góis AR, Samalyuk K, Costa F.
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
A concealed atriopleural fistula resulting from a cardiac stab wound
María Elena Arnáiz-García +7 more
openalex +1 more source
Endovenous Laser Ablation of Tributary Varicose Veins:From Stab Avulsion to Varicose Ablation
Junichi Utoh, Yoshiharu Tsukamoto
openalex +2 more sources

