Results 161 to 170 of about 188,007 (320)
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao+3 more
wiley +1 more source
GUY'S HOSPITAL. WOUND IN THE ABDOMEN FROM A STAB ; PROTRUSION OF INCISED INTESTINE ; DEATH ON THE FOLLOWING DAY [PDF]
Birkett
openalex +1 more source
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang+12 more
wiley +1 more source
Fiberoptic bronchoscopy-guided endotracheal intubation in prone position for a patient with a thoracic spinal stab wound: a case report. [PDF]
Zhou J, Zhu K, Wang C, Zhu Y.
europepmc +1 more source
Flush saphenofemoral ligation and multiple stab phlebectomy preserve a useful greater saphenous vein four years after surgery [PDF]
Louis Fligelstone+6 more
openalex +1 more source
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang+10 more
wiley +1 more source
Low-velocity penetrating trauma with anterior mitral leaflet perforation and left ventricular injury: Immediate and postoperative management. [PDF]
Kim S+4 more
europepmc +1 more source