Acute TBK1/IKK-ε Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury [PDF]
Frontiers in Aging Neuroscience, 2021 Traumatic brain injury has a poorer prognosis in elderly patients, possibly because of the enhanced inflammatory response characteristic of advanced age, known as “inflammaging.” Recently, reduced activation of the TANK-Binding-Kinase 1 (Tbk1) pathway ...
Rida Rehman +20 more
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17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury. [PDF]
Antioxidants (Basel), 2021 Disruptions in brain energy metabolism, oxidative damage, and neuroinflammation are commonly seen in traumatic brain injury (TBI). Microglial activation is the hallmark of neuroinflammation.
Saeed K +8 more
europepmc +2 more sources
Transcriptome Analyses Reveal IL6/Stat3 Signaling Involvement in Radial Glia Proliferation After Stab Wound Injury in the Adult Zebrafish Optic Tectum. [PDF]
Front Cell Dev Biol, 2021 Adult zebrafish have many neurogenic niches and a high capacity for central nervous system regeneration compared to mammals, including humans and rodents.
Shimizu Y, Kiyooka M, Ohshima T.
europepmc +2 more sources
Abdominal stab wound with an unusual presentation: A case report [PDF]
SAGE Open Medical Case ReportsThe forensic literature has described unusual wounds of entry into fatal stab wounds that are rarely found in autopsies. Stab wounds are considered fatal injuries when they occur in vital organs.
Darshan Galoria +5 more
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Transfixing heart injury by stab wound: Case report [PDF]
Trauma Case Reports, 2021 Cardiac impalement is a rare and usually fatal injury. Immediate recognition and surgical intervention are decisive factors for patient survival. This is a reported case of cardiac impalement with left ventricular transfixation, whose prehospital ...
Gabriela Tulio Struck +11 more
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Anesthetic management of stab wound in right ventricle of heart
Saudi Journal of Anaesthesia, 2019 Stab wound in right ventricle of heart requires a prompt and focused surgical intervention. Cardiac tamponade is a common finding when dealing with stabbed hearts, which must be diagnosed and treated in a timely fashion.
Muhammad Saad Yousuf, Hameed Ullah
doaj +2 more sources
p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound. [PDF]
Cell Mol Neurobiol, 2022 Chen M +6 more
europepmc +2 more sources
Dibutyryl Cyclic Adenosine Monophosphate Rescues the Neurons From Degeneration in Stab Wound and Excitotoxic Injury Models [PDF]
Frontiers in Neuroscience, 2018 Dibutyryl cyclic adenosine monophosphate (dBcAMP), a cell-permeable synthetic analog of cAMP, has been shown to induce astrogliosis in culture. However, the exact mechanism underlying how dBcAMP exerts its function in situ is not clear.
Ebtesam M. Abd-El-Basset +1 more
doaj +2 more sources
New insights on Ötzi’s injuries from a clinical perspective [PDF]
Scientific ReportsThe Tyrolean Iceman (Ötzi), discovered in the Tyrolean Alps, in 1991 is a remarkably well-preserved natural mummy estimated to be around 5300 years old, dating back to the Copper Age.
Jochen Weber +3 more
doaj +2 more sources
Thoraco-laparotomy approach to salvage a life-threatening cardiac box stab injury to the infecrior vena cava in Malaysia: a case report [PDF]
Journal of Trauma and Injury, 2023 Torso stab injuries near the cardiac box may present unique challenges due to difficulties in hemorrhage control. For a stab injury to the heart, the repair is straightforwardly performed via median sternotomy.
Ida Arinah Mahadi +4 more
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