Results 191 to 200 of about 263,021 (278)
A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders
Movement Disorders, EarlyView.Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta +6 more
wiley +1 more source
International Journal of Mechanical System Dynamics, EarlyView.ABSTRACT The design of control systems for high‐agility mechanical systems operating in extreme environments is a significant challenge in nonlinear dynamics. This paper addresses the complex dynamic control problem of a hypersonic interceptor, modeled as a multi‐input multi‐output (MIMO) mechanical system characterized by strong aerodynamic cross ...
Mohammad Mahdi Soori +1 more
wiley +1 more source
Emergencies in Amyotrophic Lateral Sclerosis
Muscle &Nerve, EarlyView.ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal +9 more
wiley +1 more source
Are We Overmonitoring Vestibular Schwannomas? Challenging the Necessity of Tracking Them All
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Increased MRI use for nonspecific symptoms has led to frequent detection of small or incidental vestibular schwannomas (VS), most of which never require treatment. This study aimed to develop and validate a stepwise model to stratify VS patients using early MRI findings and reduce unnecessary long‐term surveillance.
Aïna Venkatasamy +4 more
wiley +1 more source
Superficial Stab Wound to Zone I of the Neck Resulting in Thyrocervical Trunk Pseudoaneurysm Presented as Recurrent Hemothorax and Successfully Managed by Coil Embolization. [PDF]
Am J Case Rep, 2020 Elkbuli A +4 more
europepmc +1 more source
The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease
Pediatric Investigation, EarlyView.Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia +3 more
wiley +1 more source
Polymer Engineering &Science, EarlyView.Cellulose nanocrystals extracted from Mauritia flexuosa petiole were combined with MCM‐41 mesoporous silica to create a diclofenac‐loaded hybrid nanocomposite. Incorporation into electrospun PVA scaffolds enabled controlled diclofenac release and high cell viability, highlighting their potential for localized drug delivery.
Karoliny V. Barbosa +11 more
wiley +1 more source
Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex. [PDF]
Nat CommunKoupourtidou C +13 more
europepmc +1 more source