Results 251 to 260 of about 680,783 (346)

Out There No One Has a Right to Die

Bioethics, EarlyView.
ABSTRACT The eventual goal of space exploration is to colonize exoplanets and their moons outside our solar system. This is a dangerous and immoral endeavour. The extraterrestrial life forms encountered would be hostile, vulnerable or both, and the descendants of the original pioneers would be involuntarily exposed to hazardous conditions and ...
Matti Häyry
wiley   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Hepatic sepsis: Generally applicable lessons learned from liver transplantation [PDF]

, 1975
Putnam, CW, Starzl, TE
core  

Duration‐Dependent Efficacy and Clinical Safety of Repeated Low‐Level Red‐Light Therapy for Paediatric Myopia: A Systematic Review and Meta‐Analysis

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Repeated low‐level red‐light (RLRL) therapy is a novel, non‐invasive intervention for controlling paediatric myopia progression. Despite increasing clinical use, questions remain regarding the magnitude, durability, and safety of treatment effects.
Lee‐Yuan Lin, Cheng‐Hao Hsu, Hung Su, Jia‐Wei Sun, Jie‐Syuan Wu, Wei‐Jung Jeng, Chen‐Hsin Tsai, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +8 more
wiley   +1 more source

Comparison of Piezoelectric and High‐Speed Drills for Frontal Beak Osteotomy in Endoscopic Sinus Surgery—Exploratory Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Frontal beak reduction is a critical and challenging step in endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). Traditional high‐speed drills can risk thermal injury and soft tissue trauma, whereas piezoelectric surgery uses ultrasonic vibrations for selective bone cutting and may improve surgical precision.
Łukasz Skrzypiec, Kornel Szczygielski, Agnieszka Brociek‐Piłczyńska, Dariusz Jurkiewicz, Marta Aleksandra Kwiatkowska   +4 more
wiley   +1 more source

Serum lipids and anticonvulsants [PDF]

, 1982
Berlit, Peter, Heuck, C. C., Krause, Klaus-Henning, Schellenberg, Bernhard   +3 more
core  

Recurrent self-inflicted abdominal stab injuries leading to isolated Meckel's diverticulum perforation: A surgical case report and literature-backed review. [PDF]

Ulus Travma Acil Cerrahi Derg
Türker B, Kurtkulağı Ö, Karacaer MA, Gökten G, Kaya M.   +4 more
europepmc   +1 more source

Knife crime : the government reply to the seventh report from the Home Affairs Committee, Session 2008-09, Hc 112 [PDF]

, 2009

core