Results 71 to 80 of about 608,567 (368)

Ultrasound‐Induced Nitric Oxide‐Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime

Advanced Science, EarlyView.
A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu, Jinxu Cao, Yan Mu, Hao Zhang, Ya‐Lei Wang, Mengzhen Chen, Yuce Li, Qian Hua   +7 more
wiley   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Sub-pm/$\mathrm{\mathbf{\sqrt{\rm Hz}}}$ non-reciprocal noise in the LISA backlink fiber

, 2017
The future space-based gravitational wave detector Laser Interferometer Space Antenna (LISA) requires bidirectional exchange of light between its two optical benches on board of each of its three satellites.
Danzmann, Karsten, Diekmann, Christian, Fleddermann, Roland, Heinzel, Gerhard, Steier, Frank, Tröbs, Michael   +5 more
core   +1 more source

Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]

, 1992
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
A Nerlich, A Vaheri, A. Nerlich, AE Postlethwaite, DF Mosher, E Boehm, E Linder, E Ruoslahti, E Ruoslahti, EA Jaffee, F Grinnell, F Grinnell, F Jilek, H Hormann, H Hormann, I. Wiest, J Raekallio, J Raekallio, J Viljanto, J. Tübel, J. Wilskel, K Alitalo, KM Yamada, LA Repesh, M Kurkinen, M Oehmichen, M Oehmichen, MW Mosesson, P Betz, P Davison, P. Betz, R Jarecki, R. Penning, RAF Clark, RAF Clark, S Berg, S Berg, S Berg, S Stenman, SM Hsu, St Niewiarowski, V Schneider, W Eisenmenger, W. Eisenmenger   +43 more
core   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

Penetrating Abdominal Injury by a Large Stone [PDF]

, 2012
Penetrating trauma can be commonly caused by sharp objects. We report a case of penetrating injury of abdomen caused by a fairly large sized stone which is used for sharpening the objects or weapons.
Baitha, K, Kamble, AT, Kaple, MN, Mahakalkar, CC   +3 more
core  

Intravenous general anesthesia in the prone position for a patient with a stab wound

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
The position of the patient has an important role in facilitating the development of a surgical intervention. In the case of patients with a stab, the wound can limit the possibilities while positioning the patient.
Karell Piñón-García, Yudelky Almeida-Esquivel, Mayda Correa-Borrell   +2 more
doaj  

How to mend a broken heart: a major stab wound of the left ventricle

World Journal of Emergency Surgery, 2012
A 28-year-old male admitted with a stab wound under his left nipple, underwent emergency surgery because of confusion, a decreasing blood pressure and increasing tachycardia.
M. Kaljusto, T. Tønnessen
semanticscholar   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source