Results 81 to 90 of about 39,352 (358)
Recurrent violent injury: magnitude, risk factors, and opportunities for intervention from a statewide analysis. [PDF]
INTRODUCTION: Although preventing recurrent violent injury is an important component of a public health approach to interpersonal violence and a common focus of violence intervention programs, the true incidence of recurrent violent injury is unknown ...
Crandall, Marie L.+5 more
core +2 more sources
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Stabbing Pairwise Intersecting Disks by Four Points [PDF]
In their seminal work, Danzer (1956, 1986) and Stach\'{o} (1981) established that every set of pairwise intersecting disks in the plane can be stabbed by four points. However, both these proofs are non-constructive, at least in the sense that they do not seem to imply an efficient algorithm for finding the stabbing points, given such a set of disks $D$.
arxiv
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang+12 more
wiley +1 more source
Journal ArticleMicrophacoemulsification, or cataract surgery using ultrasound through two small stab incisions.
Olson, Randall J.
core
Neuro-inflammation is associated with the production of cytokines, which influence neuronal and glial functions. Although the proinflammatory cytokines interferon-γ (IFN-γ) and interleukin-1Beta (IL-1β) are thought to be the major mediators of neuro ...
Ebtesam M Abd-El-Basset+2 more
doaj +1 more source
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska+18 more
wiley +1 more source
Wound pH depends on actual wound size [PDF]
Wound healing is an intricate process that involves many types of cells, reaction pathways as well as chemical, physical and electrical cues. Since biochemical reactions and physiological events are pH-dependent we study here pH as an important major characteristic of the wound healing process in the presence of endogenous and exogenous electric fields.
arxiv
Stabbing balls with line segments and polygonal paths [PDF]
We study the problem of ordered stabbing of $n$ balls (of arbitrary and possibly different radii, no ball contained in another) in $\mathbb{R}^d$, $d \geq 3$, with either a directed line segment or a (directed) polygonal curve. Here, the line segment, respectively polygonal curve, shall visit (intersect) the given sequence of balls in the order of the ...
arxiv