Results 91 to 100 of about 294,593 (286)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Flexible inflation targeting and financial stability: Is it enough to stabilise inflation and output? [PDF]

open access: yes
We investigate empirically whether a central bank can promote financial stability by stabilising inflation and output, and whether additional stabilisation of asset prices and credit growth would enhance financial stability, in particular.
Q. Farooq Akram, Øyvind Eitrheim
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Unione monetaria e politica di stabilizzazione nella Comunità Europea.

open access: yesMoneta e Credito, 2014
A plan for European Monetary Union was recently proposed based on the issue of a parallel European currency, the acceptance of which would be established by a market process, not by official edicts and which would be managed to achieve stable European ...
M. PARKIN
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Commodity price stabilisation and the developing countries

open access: yesPSL Quarterly Review, 2014
Developing countries have, for more than two decades, emphasised the adverse impact of prices and export revenue fluctuations on their economies.
E. BROOK, E. GRILLI, J. WAELBROECK
doaj   +1 more source

Editorial: Do Stabilisation Policies Stabilise? [PDF]

open access: yesIDS Bulletin, 1988
Christopher Colclough   +1 more
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Monetary union and stabilization policy in the European Community

open access: yesPSL Quarterly Review, 2014
A plan for European Monetary Union was recently proposed based on the issue of a parallel European currency, the acceptance of which would be established by a market process, not by official edicts and which would be managed to achieve stable European ...
M. PARKIN
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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