Results 61 to 70 of about 115,324 (300)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Stabilizzazione dei prezzi di prodotti primari e paesi in via di sviluppo

open access: yesMoneta e Credito, 2014
Developing countries have, for more than two decades, emphasised the adverse impact of prices and export revenue fluctuations on their economies.
E. BROOK, E. GRILLI, J. WAELBROECK
doaj   +1 more source

Moduli stabilisation on the worldsheet [PDF]

open access: yesJournal of High Energy Physics, 2011
We consider compactifications of type II string theory using exact internal CFT's with central charge $c=9+ε$, $|ε| \ll 1$, leading to an effective potential for the dilaton. For $ε>0$ the potential is positive and the dilaton is ultimately driven to weak coupling.
Deo, Jawad   +2 more
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

On stabilisation policy: Are there conflicting implications for growth and welfare? [PDF]

open access: yes
The paper examines the choices for fiscal stabilisation policy that maximise aggregate welfare and long-run growth. This is done in the context of a stochastic dynamic general equilibrium model where premeditated learning provides the engine of human ...
Dimitrios Varvarigos
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Government size and output volatility: should we forsake automatic stabilisation? [PDF]

open access: yes
In this working paper, Xavier Debrun, Jean Pisani-Ferry and André Sapir explore the relationships between government size and output volatility. Whilst government size contributes to macroeconomic stabilisation, the slow down in output volatility of the ...
Xavier Debrun   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The Effect of Regular Exercising on Shoulder Pain and Scapular Endurance

open access: yesAhi Evran Medical Journal
Purpose: Serratus Anterior and Trapezius muscles are the most important stabilizers of the scapulothoracic joint. Inadequate endurance of these muscles plays a crucial role in reduced neuromuscular performance.
Aziz Dengız   +2 more
doaj   +1 more source

Monetary Stabilisation Policy and Long-run Growth [PDF]

open access: yes
This paper presents a stochastic monetary growth model with nominal rigidities and active monetary policy in which technological change contains both deliberate (internal) and serendipitous (external) learning mechanisms.
Galindev Ragchaasuren
core  

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