Results 91 to 100 of about 193,302 (282)

UV-enhanced sacrificial layer stabilised graphene oxide hollow fibre membranes for nanofiltration [PDF]

, 2015
Graphene oxide (GO) membranes have demonstrated great potential in gas separation and liquid filtration. For upscale applications, GO membranes in a hollow fibre geometry are of particular interest due to the high-efficiency and easy-assembly features at
Aba, NFD, Chong, JY, Li, K, Mattevi, C, Wang, B   +4 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Sintering and characterisation of nano-sized yttria-stabilised zirconia [PDF]

, 2006
A study has been conducted on the pressure-less sintering of the ZrC>2- Y2O3 system that contains 3 mol% Y2O3, and the effect that the temperature / time relationship has on the properties of the final product.
Hasanuzzaman, Mohammed
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Evaluating Different Track Sub-Ballast Solutions Considering Traffic Loads and Sustainability

Infrastructures
The railway industry is seeking high-performance and sustainable solutions for sub-ballast materials, particularly in light of increasing cargo transport demands and climate events.
Guilherme Castro, Jonathan Saico, Edson de Moura, Rosangela Motta, Liedi Bernucci, André Paixão, Eduardo Fortunato, Luciano Oliveira   +7 more
doaj   +1 more source

Stabilisation of Seven Directions in an Early Universe M -- theory Model

, 2009
Our model consists of intersecting 22'55' branes in M theory distributed uniformly in the common transverse space. Equations of state follow from U duality symmetries.
Bhowmick, Samrat, Digal, Sanatan, Rama, S. Kalyana   +2 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A general purpose stabilised balloon platform [PDF]

The development of a three axis stabilized balloon platform capable of being operated in three modes of increasing accuracy is discussed. The system relies on angular motion sensing for primary feedback with linear accelerometers, magnetometers, and a ...
How, J.
core   +1 more source