Results 161 to 170 of about 55,649 (312)

Cow-dung stabilised compressed earth blocks: a mechanistic approach to understand its water resistance behaviour. [PDF]

Mater Struct
Kulshreshtha Y, Vardon PJ, Meesters GMH, van Loosdrecht MCM, Mota NJA, Jonkers HM.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Allene synthesis via boron-stabilised alkenyl carbanions

A new allene synthesis involving the boron-Wittig reaction of aldehydes with boron-stabilised carbanions is disclosed its scope and limitations are ...
Pelter, Andrew, Jones, Kevin D., Smith, Keith   +2 more
core   +1 more source

Medial-pivot total knee arthroplasty demonstrates more constrained mid-flexion gait kinematics than posterior-stabilised total knee arthroplasty under standardised soft-tissue balancing: A randomised controlled trial with a healthy reference cohort. [PDF]

J Exp Orthop
Nakamura E, Okamoto N, Masuda T, Hisanaga S, Yugami M, Oniki Y, Miyamoto T.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Strength and Durability Properties of Cow Dung Stabilised Earth Brick

, 2013
This research, reports on the investigation into the strength and the durability properties of earth brick stabilised with Cow dung. A local earth was stabilised chemically by Cow dung.
Yalley, Peter Paa-Kofi, Manu, Dorothy
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The test-retest reliability and agreement between a fixed frame and belt-stabilised handheld dynamometer for isometric hip flexion and extension peak force measurement in recreational cyclists. [PDF]

PLoS One
D'Mello D, Digweed B, Hughes T.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Durability testing of fine grained stabilised soils

Lime and/or cement stabilised fine-grained soils have been successfully used in the construction industry throughout the UK since the early 1970’s. Soil stabilisation has several economic, technical and environmental advantages.
Notman, C.F.
core