Results 91 to 100 of about 70,466 (298)

1, 3-Dipolar cycloaddition of stabilised and non-stabilised azomethine ylides derived from uracil polyoxin C (UPoC): access to nikkomycin anologues

open access: yes, 2004
Cascade thermal and decarboxylative cycloaddition reactions of uracil polyoxin C (UPoC) with mono- and di-carbonyl compounds in the presence of a dipolarophile leads, via stabilised and non-stabilised azomethine ylides respectively, to a series of ...
Fishwick, CWG   +3 more
core   +1 more source

Modelling and control of the roll-stabilised control unit of a rotary steerable system directional drilling tool

open access: yesThe Journal of Engineering, 2019
A directional drilling tool control unit whose design is based on servo control of a rotary valve using the roll-stabilised instrumented system approach has been successfully used in oil fields for over 20 years.
Hamid Alturbeh   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

BslA-stabilised emulsion droplets with designed microstructure

open access: yes, 2016
Original microscope images of BslA-stabilised emulsion droplets and two time-lapse confocal microscope sequences (available to view using ImageJ imaging software) of BslA-stabilised partially coalesced droplets melting in the absence and presence of free
School of Physics and Astronomy   +2 more
core   +1 more source

Effect of phosphogypsum on strength of lime stabilized expansive soil

open access: yesGrađevinar, 2014
The use of phosphogypsum as an additive to lime, to enhance its performance in soil stabilization, is analysed in this paper. The phosphogypsum is a by-product of the phosphate rock processing during production of phosphoric acid.
P. Kasinatha Pandian, Jijo James
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Early metal bis(phosphorus-stabilised)carbene chemistry

open access: yes, 2011
Since the discovery of covalently-bound mid- and late-transition metal carbenes there has been a spectacular explosion of interest in their chemistry, but their early metal counterparts have lagged behind.
Stephen T. Liddle   +5 more
core   +1 more source

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