Results 211 to 220 of about 10,939,833 (368)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Elevated CO₂ and N Gradually Weaken the Influence of Diversity on Ecosystem Stability. [PDF]

Ecol Lett
Mohanbabu N, Isbell F, Hobbie SE, Reich PB.   +3 more
europepmc   +1 more source

A THEORETICAL AND EXPERIMENTAL STUDY OF THE MOTION AND STABILITY OF CERTAIN ATMOSPHERIC VORTICES [PDF]

, 1951
Robert R. Long
openalex   +1 more source

Relationship of core self-evaluations traits--self-esteem, generalized self-efficacy, locus of control, and emotional stability--with job satisfaction and job performance: a meta-analysis.

Journal of Applied Psychology, 2001
T. Judge, J. Bono
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Structural stability estimated through critical perturbation determines evolutionary persistence in mutualistic model ecosystems. [PDF]

R Soc Open Sci
Lurgi M, Pascual-García A.
europepmc   +1 more source

THE STABILITY OF BACTERIAL SUSPENSIONS [PDF]

, 1923
John H. Northrop
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Seismic slope stability analysis using modified pseudo dynamic method with uniform random field of initial phases. [PDF]

PLoS One
Xu L, Jing H, Wen J, Li L, Song Z.
europepmc   +1 more source

The stability constant of the Tris-1,10-phenanthroline ferrous ion [PDF]

, 1955
HA McKenzie
openalex   +1 more source