Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Digital governance, anti-corruption and political stability: An empirical study using cross-national panel data. [PDF]
Zhao Y, Du Z.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Study on Stability of Remifentanil, Sufentanil, and Their Metabolites in Human Whole Blood and Urine. [PDF]
Wang Z +14 more
europepmc +1 more source
Stability-guided treatment of pediatric radial neck fractures: percutaneous reduction with cast immobilization versus elastic intramedullary nailing. [PDF]
Yang YH +8 more
europepmc +1 more source
A yield design approach to the stability analysis of A seabed subjected to wave loading and pseudo-static seismic forces. [PDF]
Quiuqui JPC, Maghous S.
europepmc +1 more source
Intelligent particle filtering state observer for stability assessment in solar-wind penetrated microgrids. [PDF]
Alharbi A.
europepmc +1 more source

