Results 31 to 40 of about 7,887,454 (271)

The Stability study: a protocol for a multicenter randomized clinical trial comparing anterior cruciate ligament reconstruction with and without Lateral Extra-articular Tenodesis in individuals who are at high risk of graft failure

BMC Musculoskeletal Disorders, 2019
Background The purpose of anterior cruciate ligament reconstruction (ACLR) is to restore stability to the knee. Persistent rotational laxity following ACLR has been correlated with poor outcome and graft failure. We hypothesize that anterolateral complex
Alan Getgood, Dianne Bryant, Andrew Firth, Stability Group   +3 more
doaj   +1 more source

Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells

Nature Communications, 2023
DNA replication stress can generate under-replicated DNA regions which is fixed by an atypical form of DNA repair synthesis in mitosis (MiDAS). Here the authors show that translesion and replicative DNA polymerases cooperate via the POLD3 subunit to ...
Wei Wu, Szymon A. Barwacz, Rahul Bhowmick, Katrine Lundgaard, Marisa M. Gonçalves Dinis, Malgorzata Clausen, Masato T. Kanemaki, Ying Liu   +7 more
doaj   +1 more source

Stochastic Stability

, 2000
In this talk I will introduce the principle of stochastic stability and discussing its consequences both at equilibrium and off-equilibrium.Comment: Proceedings of the Conference Disordered and Complex Systems, London July 2000 7 pages and 3 ...
Parisi, Giorgio
core   +2 more sources

From Design to Implementation: Addressing the Causes of Violent Conflict in Nigeria

Stability : International Journal of Security and Development, 2014
This article considers the ways in which knowledge and research influenced the design of a programme to reduce violent conflict in Nigeria. The diversity of sources and forms of conflict in Nigeria, and the way that local grievances interact ...
Judy El-Bushra, Sarah Ladbury, Ukoha Okorafor Ukiwo   +2 more
doaj   +1 more source

Immune Checkpoints in Viral Infections

Viruses, 2020
As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system ...
Huiming Cai, Ge Liu, Jianfeng Zhong, Kai Zheng, Haitao Xiao, Chenyang Li, Xun Song, Ying Li, Chenshu Xu, Haiqiang Wu, Zhendan He, Qinchang Zhu   +11 more
doaj   +1 more source

Symplectic stability, analytic stability in non-algebraic complex geometry

, 2003
We give a systematic presentation of the stability theory in the non-algebraic Kaehlerian geometry. We introduce the concept of "energy complete Hamiltonian action".
Teleman, Andrei
core   +4 more sources

Chatter milling modeling of active magnetic bearing spindle in high-speed domain [PDF]

, 2011
A new dynamical modeling of Active Magnetic Bearing Spindle (AMBS) to identify machining stability of High Speed Milling (HSM) is presented. This original modeling includes all the minimum required parameters for stability analysis of AMBS machining. The
Arnaud, Lionel, Gourc, Etienne, Seguy, Sébastien   +2 more
core   +4 more sources

Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex

Nature Communications
The BTRR (BLM/TOP3A/RMI1/RMI2) complex resolves DNA replication and recombination intermediates to maintain genome stability. Alongside PICH, they target mitotic DNA intertwinements, known as ultrafine DNA bridges, facilitating chromosome segregation ...
María Fernández-Casañas, Eleftheria Karanika, Umit Aliyaskarova, Tomisin Olukoga, Alex D. Herbert, Antony W. Oliver, Matthew Day, Adrijana Crncec, Kok-Lung Chan   +8 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source