Results 151 to 160 of about 5,604,642 (305)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Stability analysis and noise reduction of a cone-type poppet valve in an aero-hydraulic system. [PDF]

Sci Rep
Chen W, Chen Y, Xu Y, Zhang L.
europepmc   +1 more source

A study on stability analysis of atrial repolarization variability using ARX model in sinus rhythm and atrial tachycardia ECGs

, 2016
J. Sivaraman, G. Uma, Philip Langley, M. Umapathy, S. Venkatesan, G. Palanikumar   +5 more
openalex   +2 more sources

An Analysis Of Stability Behaviour For Two Preys And Two Predators Ecological Model

, 2023
A.M. Sarravanaprabhu, M. Gunasekaran
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Stability analysis of heterogeneous oligopoly games of increasing players: A computational approach. [PDF]

PLoS One
Hou R, Li X, Wan W.
europepmc   +1 more source

Numerical stability analysis and flow simulation of lid-driven cavity subjected to high magnetic field

, 2016
Luca Marioni, François Bay, Elie Hachem
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Seismic stability analysis of cracked compound slopes considering soil heterogeneity. [PDF]

Sci Rep
Jin L.
europepmc   +1 more source

Stability analysis of RNAtranslator generated RNAs compared to natural RNAs.

Sobhan Shukueian Tabrizi (22367524), Sina Barazandeh (22094174), Helyasadat Hashemi Aghdam (22367527), A. Ercument Cicek (9629154)   +3 more
openalex   +1 more source