Results 111 to 120 of about 569,907 (264)
Impact of vibrations on machining quality and tool wear during metal cutting
Наукові доповіді Національного університету біоресурсів і природокористування УкраїниThe purpose of this study was to comprehensively assess the effect of vibration load on the wear rate of the cutting tool, the stability of the cutting process, the thermal characteristics of the contact zone, and the quality of the machined surface ...
O. Bryniuk, Ya. Hrechaniuk
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Scientia AgricolaThe mesoregions of Campo das Vertentes and South/Southwest of Minas in southern Minas Gerais state are important wheat crop areas characterized by substantial macroenvironmental diversity.
Ricardo Antonio Ruiz-Cardozo +10 more
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Revised Stability Scales of the Postural Stability Index for Human Daily Activities. [PDF]
Entropy (Basel), 2020 Chang YP, Jiang BC, Nurwulan NR.
europepmc +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Evaluation of equivalent reactions in women after mastectomy using biodex balance system
Journal of Education, Health and Sport, 2017 Introduction: Breast cancer is the most commonly diagnosed malignant tumour in women in Poland, as well as in developed countries of the world. The unilateral radical mastectomy may result in disturbance of statics and body balance.
Magdalena Kabała, Jacek Wilczyński
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source