Results 51 to 60 of about 569,907 (264)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Exploring the spatial variation of intra-urban housing prices based on inverse S-function fitting of 35 cities

Frontiers in Built Environment
Housing prices serve as a crucial indicator of macroeconomic stability and urban spatial vitality. However, existing studies on intra-urban housing prices predominantly focus on single-city empirical analyses or localized examinations of individual ...
Xiaojin Liang, Xiaojin Liang, Xiaojin Liang, Xiaojin Liang, Tianqi Qiu, Tianqi Qiu, Tianqi Qiu, Bingbing Jin, Bingbing Jin, Bingbing Jin, Jiehong Lin, Jiehong Lin, Jiehong Lin, Shihan Guo   +13 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Changes in Trunk Variability and Stability of Gait in Patients with Chronic Low Back Pain: Impact of Laboratory versus Daily-Living Environments

Journal of Pain Research, 2021
Yuki Nishi,1,2 Hayato Shigetoh,1 Ren Fujii,1 Michihiro Osumi,1,3 Shu Morioka1,3 1Department of Neurorehabilitation, Graduate School of Health Science, Kio University, Nara, Japan; 2Department of Rehabilitation Medicine, Nishiyamato Rehabilitation ...
Nishi Y, Shigetoh H, Fujii R, Osumi M, Morioka S   +4 more
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Assessing Stability and Correlations Among Cotton Seed Quality Traits Across Multiple Environments Using the Stability Index

Applied Sciences
The stability of seed quality traits is a key factor for developing reliable cotton cultivars with consistent performance across diverse environments.
Vasileios Greveniotis, Elisavet Bouloumpasi, Adriana Skendi, Dimitrios Kantas, Constantinos G. Ipsilandis   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Preserved auditory-motor synchronization during finger-tapping to music and metronomes at various tempi in progressive multiple sclerosis

Frontiers in Neurology
BackgroundPersons with relapsing and remitting multiple sclerosis (MS) can synchronize steps with music and metronomes at different tempi. However, progressing demyelination, loss of neural connectivity and increased cognitive impairment likely affects ...
Nele Vanbilsen, Nele Vanbilsen, Peter Feys, Peter Feys, Mattia Rosso, Bart Van Wijmeersch, Bart Van Wijmeersch, Daphne Kos, Daphne Kos, Marc Leman, Sonja A. Kotz, Lousin Moumdjian, Lousin Moumdjian, Lousin Moumdjian   +13 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source