Results 101 to 110 of about 861,879 (285)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The Incorporation of Truncated Fourier Series into Finite Difference Approximations of Structural Stability Equations [PDF]
A new trigonometric approach to the finite difference calculus was applied to the problem of beam buckling as represented by virtual work and equilibrium equations.
Hannah, S. R., Palazotto, A. N.
core +1 more source
The asymptotic stability of difference equations
Applied Mathematics Letters, 2000 The paper discusses the stability properties of the linear delay difference equation \[ x_{n+1}-x_n=-a_nx_{n-k} , \tag{1} \] where \(a_n\geq 0\) and \(k\geq 1\). As the main result it is proved that if \[ \sum_{n=0}^{\infty}a_n=\infty \tag{"(C1)"} \] and \[ \underset{n\to\infty}\limsup \sum_{j=n-2k}^{n-1 ...
openaire +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Stability analysis of a system of second order rational difference equations [PDF]
Computational Ecology and Software, 2020 In this paper we consider a system of second order rational difference equations. We mainly discuss the boundedness and persistence, existence of fixed point, and uniqueness of positive fixed point, local and global behavior of positive fixed point and ...
Muhammad Salman Khan +3 more
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Viscous instability of a compressible round jet
, 2007 The compressible linear stability equations are derived from the Navier Stokes equations in cylindrical polar coordinates. Numerical solutions for locally parallel flow are found using a direct matrix method. Discretization with compact finite difference
Salgado, Adriana M., Sandham, Neil D.
core
Hyers-Ulam Stability of Fractional Nabla Difference Equations [PDF]
International Journal of Analysis, 2016 We investigate the Hyers-Ulam stability, the generalized Hyers-Ulam stability, and the Fα-Hyers-Ulam stability of a linear fractional nabla difference equation using discrete Laplace transform. We provide a few examples to illustrate the applicability of established results.
openaire +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source