Results 231 to 240 of about 10,543,643 (302)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Stable Across Time and Targets? Test-Retest Reliability of the Emotional Accuracy Test. [PDF]

J Intell
Israelashvili J.
europepmc   +1 more source

Influence of Implant Macrogeometry on Primary Stability in Different Polyurethane Bone-Density Models: An In Vitro Study. [PDF]

Bioengineering (Basel)
Tumedei M, Graziani U, Cipollina A, Ori R, Piattelli A, Covani U, Enia L, Pitruzzella C, Mangione F.   +8 more
europepmc   +1 more source

Arthroscopic Diagnosis and All-Inside Repair of Meniscofibular Ligament Tear. [PDF]

Arthrosc Tech
Grassi A, Cerasoli T, Rinaldi VG, Rossi C, Marcheggiani Muccioli GM, Zaffagnini S.   +5 more
europepmc   +1 more source