Results 11 to 20 of about 103,434 (195)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Survey on Continuous Time Computations [PDF]

, 2007
We provide an overview of theories of continuous time computation. These theories allow us to understand both the hardness of questions related to continuous time dynamical systems and the computational power of continuous time analog models.
A Ben-Hur, A Ben-Hur, A Ben-Hur, A Ben-Hur, A Kempe, A Rabinovich, A Turing, A Vergis, A. Church, APL Francisco, Asarin, B Trakhtenbrot, BJ Copeland, C Moore, C Moore, C Moore, C Moore, CE Shannon, CS Calude, D Dee, D Deutsch, D Graça, D Woods, DS Graça, DS Graça, E Asarin, E Asarin, E Asarin, E Post, EB Davies, G Etesi, G Lafferriere, G P ăun, H Abdi, HM Stoll, HT Siegelmann, HT Siegelmann, HT Siegelmann, I Artobolevskii, I Németi, J Earman, J Foy, J Mycka, J Mycka, J Mycka, J Mycka, J Šíma, J Šíma, JF Costa, JJ Hopfield, JJ Hopfield, JV Tucker, K Ruohonen, K Ruohonen, K Ruohonen, K Ruohonen, K Ruohonen, K Ruohonen, K Weihrauch, K-I Ko, K-I Ko, L Blum, L Faybusovich, L Faybusovich, L Lipshitz, LA Rubel, LA Rubel, LM Adleman, M Campagnolo, M Campagnolo, M Casey, M Casey, M Davis, M Gori, M Hogarth, M Hogarth, M Hoyrup, M Pour-El, MB Pour-El, MB Pour-El, MB Pour-El, MD Bowles, ML Campagnolo, ML Campagnolo, ML Hogarth, MO Rabin, MS Branicky, MS Branicky, N Müller, O Bournez, O Bournez, O Bournez, O Bournez, O Bournez, O. Finkel, P Bouyer, P Clote, P Collins, P Koiran, P Koiran, P Koiran, P Orponen, P Orponen, PW Shor, R Alur, R Alur, R Legenstein, RJ Lipton, RW Brockett, RW Brockett, S Aaronson, S Grigorieff, S Omohundro, S. C. Kleene, T Brihaye, T Brihaye, T Head, T Natschläger, TA Henzinger, TD Kieu, U Helmke, V Bush, VD Blondel, VD Blondel, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, W Maass, WD Smith, Šíma   +138 more
core   +5 more sources

Selection theorem for systems with inheritance

, 2007
The problem of finite-dimensional asymptotics of infinite-dimensional dynamic systems is studied. A non-linear kinetic system with conservation of supports for distributions has generically finite-dimensional asymptotics.
Gorban, A. N.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Synchronization time in a hyperbolic dynamical system with long-range interactions

, 2010
We show that the threshold of complete synchronization in a lattice of coupled non-smooth chaotic maps is determined by linear stability along the directions transversal to the synchronization subspace.
Anteneodo, Batista, Beck, Boccaletti, Cencini, de S. Pinto, Grebogi, Katok, Kawamura, Lai, Nagai, Palaniyandi, Pecora, Pecora, Pecora, Pereira, Pikovsky, Press, Raghavachari, Rodrigo F. Pereira, Roy, Sandro E. de S. Pinto, Sergio R. Lopes, Viana, Viana, Wiesenfeld   +25 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Dynamical systems and categories

, 2013
We study questions motivated by results in the classical theory of dynamical systems in the context of triangulated and A-infinity categories. First, entropy is defined for exact endofunctors and computed in a variety of examples.
Dimitrov, George, Haiden, Fabian, Katzarkov, Ludmil, Kontsevich, Maxim   +3 more
core   +1 more source

Stability analysis of cosmological models through Liapunov's method [PDF]

, 2001
We investigate the general asymptotic behaviour of Friedman-Robertson-Walker (FRW) models with an inflaton field, scalar-tensor FRW cosmological models and diagonal Bianchi-IX models by means of Liapunov's method.
Ana Nunes, Chimento L P, Heusler M, Hirsch M W, José P Mimoso, Kolb E W, Rouche N, Ryan M P, Sudarsky D, Tiago C Charters, Wainright J, Wald R M   +11 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source