Results 61 to 70 of about 1,170,217 (311)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Stabilization of Discrete-Time Control Systems with Multiple State Delays

open access: yesAdvances in Difference Equations, 2009
We give sufficient conditions for the exponential stabilizability of a class of perturbed time-varying difference equations with multiple delays and slowly varying coefficients. Under appropiate growth conditions on the perturbations, combined with the "
Rigoberto Medina
doaj  

Stable and quadratic-optimal parallel-distributed-compensation controller design for time-varying Takagi–Sugeno fuzzy model System: A complementary computational approach

open access: yesMeasurement + Control, 2022
A complementary computational approach is proposed for the time-varying Takagi–Sugeno fuzzy model system (TVTSFMS). The proposed approach integrates orthogonal-functional approach (OFA), hybrid Taguchi genetic algorithm (HTGA), and a stabilizability ...
Fu-I Chou, Wen-Hsien Ho
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Optimal Control of Linear Impulsive Antiperiodic Boundary Value Problem on Infinite Dimensional Spaces

open access: yesDiscrete Dynamics in Nature and Society, 2010
A class of optimal control problems for infinite dimensional impulsive antiperiodic boundary value problem is considered. Using exponential stabilizability and discussing the impulsive evolution operators, without compactness and exponential stability of
JinRong Wang, YanLong Yang
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Stability, stabilizability and exact controllability of a class of linear neutral type systems [PDF]

open access: yes, 2009
Linear systems of neutral type are considered using the infinite dimensional approach. The main problems are asymptotic, non-exponential stability, exact controllability and regular asymptotic stabilizability.
Rabah, Rabah, Sklyar, Grigory M.
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stabilizability of fractional dynamical systems

open access: yesFractional Calculus and Applied Analysis, 2014
In this paper, we establish that the controllability and observability properties of fractional dynamical systems in a finite dimensional space are dual.
K. Balachandran   +3 more
semanticscholar   +1 more source

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