Results 71 to 80 of about 1,170,217 (311)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Abstract and Applied Analysis, 2012 The problem of exponential stabilization of neutral-type neural networks with various activation functions and interval nondifferentiable and distributed time-varying delays is considered.
W. Weera, P. Niamsup
doaj +1 more source
Global controllability and stabilizability of Kawahara equation on a periodic domain
, 2015 In this paper we study controllability and stabilizability of a class of distributed parameter control system described by the Kawahara equation posed on a periodic domain $\mathbb{T}$ with internal control acting on a sub-domain $\omega $ of $\mathbb{
Xiangqing Zhao, Bingyu Zhang
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Measurement Science and Instrumentation, 2011 With the aid of the spectrum technique,a new concept named α-stabilizability（0≤α≤1）is introduced and its sufficient and necessary conditions are also proposed.Especially,it is identical with the asymptotically mean square stabilizability when α=1.As an ...
Ting HOU, Wei-hai ZHANG, Hong-ji MA
doaj
Stabilization of nonlinear discrete-time systems via a digital communication channel
International Journal of Mathematics and Mathematical Sciences, 2005 We deal with the stabilization problem for a class of nonlinear discrete-time systems via a digital communication channel. We consider the case when the control input is to be transmitted via communication channels with a bit-rate constraint.
V. N. Phat, J. Jiang
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Forming Probably Stable Communities with Limited Interactions
, 2018 A community needs to be partitioned into disjoint groups; each community member has an underlying preference over the groups that they would want to be a member of. We are interested in finding a stable community structure: one where no subset of members
Igarashi, Ayumi +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source