Results 1 to 10 of about 1,260,077 (147)

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

open access: yesGenome Biology, 2019
Single-cell RNA-seq (scRNA-seq) data exhibits significant cell-to-cell variation due to technical factors, including the number of molecules detected in each cell, which can confound biological heterogeneity with technical effects.
Christoph Hafemeister, R. Satija
semanticscholar   +1 more source

Formulas for Data-Driven Control: Stabilization, Optimality, and Robustness

open access: yesIEEE Transactions on Automatic Control, 2019
In a paper by Willems et al., it was shown that persistently exciting data can be used to represent the input–output behavior of a linear system. Based on this fundamental result, we derive a parametrization of linear feedback systems that paves the way ...
Claudio De Persis, P. Tesi
semanticscholar   +1 more source

Environmental and microbial controls on microbial necromass recycling, an important precursor for soil carbon stabilization

open access: yesCommunications Earth & Environment, 2020
There is an emerging consensus that microbial necromass carbon is the primary constituent of stable soil carbon, yet the controls on the stabilization process are unknown.
Kate M. Buckeridge   +8 more
semanticscholar   +1 more source

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

open access: yesNature Communications, 2016
Extracellular interaction between programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) leads to tumour-associated immune escape. Here we show that the immunosuppression activity of PD-L1 is stringently modulated by ubiquitination ...
Chia‐Wei Li   +23 more
semanticscholar   +1 more source

RCP4.5: a pathway for stabilization of radiative forcing by 2100

open access: yes, 2011
Representative Concentration Pathway (RCP) 4.5 is a scenario that stabilizes radiative forcing at 4.5 W m−2 in the year 2100 without ever exceeding that value.
A. Thomson   +10 more
semanticscholar   +1 more source

Fundamentals of soil stabilization

open access: yesInternational Journal of Geo-Engineering, 2017
Clayey soils are usually stiff when they are dry and give up their stiffness as they become saturated. Soft clays are associated with low compressive strength and excessive settlement. This reduction in strength due to moisture leads to severe damages to
A. A. Firoozi   +3 more
semanticscholar   +1 more source

The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11.

open access: yesCancer Research, 2019
Although cell-cycle arrest, senescence, and apoptosis are established mechanisms of tumor suppression, accumulating evidence reveals that ferroptosis, an iron-dependent, nonapoptotic form of cell death, represents a new regulatory pathway in suppressing ...
Tong Liu, Le Jiang, O. Tavana, W. Gu
semanticscholar   +1 more source

Black hole metamorphosis and stabilization by memory burden [PDF]

open access: hybrid, 2020
Gia Dvali   +3 more
openalex   +1 more source

GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1 ‐dependent manner [PDF]

open access: green, 2023
Munan Shi   +14 more
openalex   +1 more source

Diminazene Aceturate Stabilizes Atherosclerotic Plaque and Attenuates Hepatic Steatosis in apoE-Knockout Mice by Influencing Macrophages Polarization and Taurine Biosynthesis [PDF]

open access: gold, 2021
Aneta Stachowicz   +11 more
openalex   +1 more source

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